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Loss of contractility and acquisition of an epithelial phenotype of vascular smooth muscle cells (VSMCs) are key events in proliferative vascular pathologies such as atherosclerosis and post-angioplastic restenosis. There is no proper cell culture system allowing VSMC differentiation so that it is d...
ORGANISM(S): Rattus norvegicus 
Role of ZHX2 in VSMCs [RNA-seq]
EP4-Tg aortic VSMCs: Control vs PGE2
We compared the global gene expression profiles of C57BL/6 mice aortas with the profiles of cultured vascular smooth muscle cells (vSMC) from the same mice, and determined whether gene responses to dioxin exposure in the vSMCs would be predictive of responses in the aorta.
ORGANISM(S): Mus musculus 
Mice VSMCs: Control vs. TNF-α cultured
Role of ZHX2 in VSMCs [Chip-seq]
Transcriptome sequencing of SLC2A10 knock-down VSMCs
Chromatin accessibilty profiling of SCA1+ and SCA1- lineage traced VSMCs
Vascular calcification (VC) is a strong predictor of cardiovascular risk, particularly in chronic kidney disease (CKD) patients, associated with increased vascular stiffness, pulse pressure, left ventricular hypertrophy and atherosclerotic plaque burden [1]. VC is currently accepted as a highly cont...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD044045 | Pride
VSMCs were cultured on Jag1 or IgG-coated plates as described above. RNA was extracted using RNA isolation kit (Qiagen). Reverse-transcription PCR was done with RNA-to-cDNA kit (Applied Biosystems). cDNA was run on a TaqMan Low-Density Array, human angiogenesis panel (Applied Biosystems , Cat#437872...
ORGANISM(S): Homo sapiens 
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