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ProteomicsDistinct interactomes of ADAR1 nuclear and cytoplasmic protein isoforms and their responses to Interferon induction
The RNA editing enzyme ADAR1, is essential for correct functioning of innate immune responses. The ADAR1p110 isoform is mainly nuclear and ADAR1p150, which is interferon inducible, is predominately cytoplasmic. Using three different approaches, co-IP with endogenous ADAR1, and Strep-tag co-IP and Bi...
ORGANISM(S): Homo sapiens (Human) 
2024-12-08 | PXD056080 | Pride
Rnase a Endo-ip Human Ifn response Adar A549 cells 
ProteomicsDistinct interactomes of ADAR1 nuclear and cytoplasmic protein isoforms and their responses to Interferon induction
Adenosine deaminase acting on RNA 1 (ADAR1), is an enzyme that catalyzes the conversion of adenosine to inosine in double-stranded RNA, a process critical for regulation of innate immune response and distinguishing between ‘self and non-self RNA’. It is expressed as two isoforms: nucleolar p110 and ...
ORGANISM(S): Homo sapiens (Human) 
2024-12-08 | PXD049991 | Pride
Human Lc-ms/ms Adar Bioid Ifn 
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