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TranscriptomicsTranscription profiling of human TLR2/1 stimulated human monocytes with the Mycobacterium tuberculosis derived 19kDa lipopeptide reveals Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
In innate immune responses, activation of Toll-like receptors (TLRs) triggers direct antimicrobial activity against intracellular bacteria, which in murine, but not human, monocytes and macrophages is mediated principally by nitric oxide. We report here that TLR activation of human macrophages up-re...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-8921 | biostudies-arrayexpress
ProteomicsPptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
Mitochondrial proteins are replete with phosphorylation; however, the origin, abundance, and functional relevance of these modifications are largely unclear. Nonetheless, mitochondria possess multiple resident phosphatases, suggesting that protein dephosphorylation may be broadly important for mitoc...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-29 | PXD012743 | Pride
Mitochondia Pptc7 Phosphoproteome 
Transcriptomicsdermatomyositis
muscle biopsies of normal and dermatomyositis patients
ORGANISM(S): Homo sapiens 
2007-08-03 | E-GEOD-1551 | biostudies-arrayexpress
UnknownPhase I Trial of the Human Double Minute 2 Inhibitor MK-8242 in Patients With Advanced Solid Tumors.
Not available
S-EPMC5946729 | biostudies-literature
TranscriptomicsFiorentino 2006-7 dermatomyositis, lupus, control skin
Background: Dermatomyositis (DM) is an autoimmune disease that mainly affects the skin, muscle, and lung. The pathogenesis of skin inflammation in DM is not well understood. Methodology and Findings: We analyzed genome-wide expression data in DM skin and compared them to those from healthy controls....
ORGANISM(S): Homo sapiens 
2012-01-12 | E-GEOD-32245 | biostudies-arrayexpress
UnknownDrivers of Variation in Opioid Prescribing after Common Surgical Procedures in a Large Multihospital Healthcare System.
Not available
S-EPMC11321601 | biostudies-literature
UnknownProspective, observational study of pain and analgesic prescribing in medical oncology outpatients with breast, colorectal, lung, or prostate cancer.
Not available
S-EPMC3383175 | biostudies-literature
UnknownLong-term outcomes of pexidartinib in tenosynovial giant cell tumors.
Not available
S-EPMC7946703 | biostudies-literature
UnknownThe lack of ADAM17 activity during embryonic development causes hemorrhage and impairs vessel formation.
Not available
S-EPMC2955552 | biostudies-literature
UnknownEvaluating Measures of Pre-ART Adherence Readiness Through Associations with ART Adherence in the Early Months of Treatment.
Not available
S-EPMC7862012 | biostudies-literature
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