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MetabolomicsComparative analysis of the adaptation of Staphylococcus aureus to internalization by different types of human non-professional phagocytic host cells (NMR assay)
Staphylococcus aureus is a human pathogen that can cause a wide range of diseases. Although formerly regarded as extracellular pathogen, it has been shown that S. aureus can also be internalized by host cells and persist within these cells. In the present study, we comparatively analyzed survival an...
2015-07-01 | MTBLS102 | MetaboLights
ProteomicsB cells sustain inflammation in human melanoma
This is the data to the melanoma-medium induction experiment. Tumor-associated and peripheral B cells from four patients were exposed to melanoma-conditioned medium (from one of the patients). This induced distinct phenotypic and functional changes in the B cells.
ORGANISM(S): Homo sapiens (Human) 
2019-10-09 | PXD011799 | Pride
Human Inflammatory tumor microenvironment Melanoma 
TranscriptomicseIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies
The amounts of eIF4G and eIF4B were decreased in the vemurafenib-treated sensitive A375 cell line. To find mechanisms behind this decrease, we sought to identify the genes whose expression changes after vemurafenib treatment in A375 cells as compared to Mel624 cells by using microarrays.
ORGANISM(S): Homo sapiens 
2014-12-30 | E-MTAB-2607 | biostudies-arrayexpress
ProteomicsMitoproteomics of neuronal mitochondria of EAE mice
Inflammation in the central nervous system (CNS) can impair the function of neuronal mitochondria and contributes to axon degeneration in the common neuroinflammatory disease multiple sclerosis (MS). Here we combine cell type-specific mitochondrial proteomics with in vivo biosensor imaging to dissec...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-18 | PXD032363 | Pride
Mitochondria Idh3 Neurons 
UnknownA high-glucose diet affects Achilles tendon healing in rats.
Not available
S-EPMC5429625 | biostudies-literature
TranscriptomicsComparative profiling in 13 muscle disease groups
Summary: Genetic disorders of muscle cause muscular dystrophy, and are some of the most common inborn errors of metabolism. Muscle also rapidly remodels in response to training and innervation. Muscle weakness and wasting is important in such conditions as aging, critical care medicine, space flig...
ORGANISM(S): Homo sapiens 
2005-10-14 | E-GEOD-3307 | biostudies-arrayexpress
UnknownRegulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats.
Not available
S-EPMC2324168 | biostudies-literature
ProteomicsQuantitative proteomics of immunocaptured mitochondria from Purkinje Cells
Mitochondria vary in morphology and function in different tissues, however little is known about their molecular diversity among cell types. To investigate mitochondrial diversity in vivo, we developed an efficient protocol to isolate cell type-specific mitochondria based on a new MitoTag mouse. We ...
ORGANISM(S): Mus musculus (Mouse) 
2019-09-03 | PXD010772 | Pride
Mitochondria Purkinje cells Neurons 
ProteomicsQuantitative proteomics of immunocaptured mitochondria from Astrocytes
Mitochondria vary in morphology and function in different tissues, however little is known about their molecular diversity among cell types. To investigate mitochondrial diversity in vivo, we developed an efficient protocol to isolate cell type-specific mitochondria based on a new MitoTag mouse. We ...
ORGANISM(S): Mus musculus (Mouse) 
2019-09-03 | PXD010781 | Pride
Astrocytes Mitochondria 
ProteomicsQuantitative proteomics of immunocaptured mitochondria from Granule cells
Mitochondria vary in morphology and function in different tissues, however little is known about their molecular diversity among cell types. To investigate mitochondrial diversity in vivo, we developed an efficient protocol to isolate cell type-specific mitochondria based on a new MitoTag mouse. We ...
ORGANISM(S): Mus musculus (Mouse) 
2019-09-03 | PXD010774 | Pride
Mitochondria Granule cells Neurons 
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