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The highly conserved Elongator complex is a translational regulator and a subject of growing interest due to its critical role in neurodevelopment, neurological diseases and brain tumors. Clinically relevant mutations have been reported in the catalytic Elp123 subcomplex, while no mutation in the ac...
ORGANISM(S): Homo sapiens (Human) 
2022-05-17 | PXD032925 | Pride
Neurodevelopmental disorders have a variety of aetiologies and most often these are complex genomic traits involving numerous mutations. Intellectual disability (ID) and autism spectrum disorder (ASD) are the most common neurodevelopmental disorders and are characterized by substantial impairment in...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-19 | PXD023653 | Pride
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