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TranscriptomicsPrediction and Testing of Novel Transcriptional Networks Regulating Embryonic Stem Cell Self-Renewal and Commitment
We have used mouse embryonic stem cells (ESCs) as a model to study the signaling mechanisms that regulate self-renewal and commitment to differentiation. We hypothesized that genes critical to stem cell fate would be dynamically regulated at the initiation of commitment. Time course microarray analy...
ORGANISM(S): Mus musculus 
2010-06-11 | E-GEOD-7520 | biostudies-arrayexpress
GenomicsGenome-wide map of PCL2 (Polycomb-like 2) enrichment in undifferentiated mouse embryonic stem cells (ESCs)
In total 8,736,191 reads from IP fraction and 9,958,984 reads from Wash fraction uniquely mapped to the mouse genome (mm9). Settings for enrichment analysis: maxSpacing=500; minHits=20; minPeakHits=6; minRatio=3. 4,701 regions have been identified as enriched in the IP fraction. In order to get a ro...
ORGANISM(S): Mus musculus 
2010-02-05 | E-GEOD-16526 | biostudies-arrayexpress
GenomicsMolecular Genetic Studies of Developmental Brain Disorders

Study 1
2R01-NS050375 (PI: DOBYNS, William B.)
The genetic basis of mid-hindbrain malformations
Our general goal for this project is to advance our understanding of human developmental disorders that involve the brainstem and cerebellum - brain structures derived from the embryoni...

phs000455.v1.p1 | EGA
ProteomicsA quantitative model for macrophage activation predicts tunable distance thresholds for propagation of inflammationes in response LPS stimulation
Label free analysis of the secretome of RAW264.7 murine macrophages in response to LPS stimulation.
ORGANISM(S): Mus musculus (Mouse) 
2015-11-30 | PXD001905 | Pride
Lps Raw264.7 murine macrophages Label free Secretome 
UnknownRTOG 9804: a prospective randomized trial for good-risk ductal carcinoma in situ comparing radiotherapy with observation.
Not available
S-EPMC4334775 | biostudies-literature
TranscriptomicsPolycomb-like 2 associates with PRC2 and is required for mouse embryonic stem cell
Polycomb group (PcG) proteins are highly conserved epigenetic transcriptional repressors important for the control of numerous developmental gene expression programs and have recently been implicated in the modulation of embryonic stem cell (ESC) identity. We identified the PcG protein PCL2 (polycom...
ORGANISM(S): Mus musculus 
2010-02-22 | E-GEOD-16364 | biostudies-arrayexpress
ProteomicsBioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative - Streptococcus pyogenes
The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (5 strains each) using an integrated application of genomic, transcriptomic, metabolomic and proteomic technologies. The pathogens included in this initiative are: Escherichia col...
ORGANISM(S): Streptoccous pyogenes 
2021-07-05 | PXD016913 | Pride
Proteomics Rpmi Swath Streptococcus pyogenes Sera Antibiotic resistance Sepsis 
ProteomicsBioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative - Staphylococcus aureus
The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (5 strains each) using an integrated application of genomic, transcriptomic, metabolomic and proteomic technologies. The pathogens included in this initiative are: Escherichia col...
ORGANISM(S): Staphylococcus aureus 
2021-07-05 | PXD016504 | Pride
Proteomics Rpmi Swath Staphylococcus aureus Sera Antibiotic resistance Sepsis 
ProteomicsBioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative - Klebsiella pneumoniae complex
The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (5 strains each) using an integrated application of genomic, transcriptomic, metabolomic and proteomic technologies. The pathogens included in this initiative are: Escherichia col...
ORGANISM(S): Klebsiella variicola Homo sapiens (Human) Klebsiella pneumoniae 
2021-07-05 | PXD016672 | Pride
Proteomics Rpmi Swath Klebsiella pneumoniae Sera Antibiotic resistance Sepsis 
UnknownPhospholemman Phosphorylation Regulates Vascular Tone, Blood Pressure, and Hypertension in Mice and Humans.
Not available
S-EPMC7969167 | biostudies-literature
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