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Aberrant DNA methylation patterns of malignant cells allow for the study of the tumor phenotype and behavior, and can be used for tumor classification. Here, we describe the genome-wide DNA methylation signatures of a T cell lymphoma that is driven by the oncogenic fusion protein NPM-ALK. Difference...
ORGANISM(S): Homo sapiens 
SCLC - Whole genome sequencing data Publication Peifer et al., 2012, Nature Genetics
SCLC - RNA sequencing data Publication Peifer et al., 2012, Nature Genetics
Small-cell lung cancer (SCLC) is an aggressive lung tumor subtype. We conducted integrated analysis of genome sequencing, transcriptome, and copy number analysis and found an extremely high mutation rate of 7.4±1 protein-changing mutations per million basepairs. Evidence for inactivation of TP53 and...
SNP 6.0 arrays of small cell lung cancer
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