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UnknownOvarian cancer stem cells: Can targeted therapy lead to improved progression-free survival?
Not available
S-EPMC4172672 | biostudies-literature
UnknownAssociation of interleukin-6 and interleukin-10 genotypes with radiographic damage in rheumatoid arthritis is dependent on autoantibody status.
Not available
S-EPMC2435416 | biostudies-literature
ProteomicsHX mapping of the binding interface between a DCP and murine LRRC-15
This dataset is associated with the manuscript titled: Development and Structural Characterization of LRRC15-binding Disulfide-Constrained Peptides for Enhanced Tumor Imaging Authors: Benjamin J. Tombling, Fei Cai, Tim Wendorff, Annie Ogasawara, Herman S. Gill, Jeff N. Tinianow, Andrew Chang, Aaron ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2026-02-20 | MSV000100920 | MassIVE
UnknownPharmacological EZH2 inhibition combined with retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells.
Not available
S-EPMC10588044 | biostudies-literature
ProteomicsFungal COP9 signalosome assembly requires connection of two trimeric intermediates for integration of intrinsic deneddylase
The eight-subunit COP9 signalosome (CSN complex), controls the exchange of E3 ubiquitin cullin RING ligase receptors through its deneddylase activity, providing specificity to eukaryotic protein degradation. The conserved eight-subunit CSN complex is required for multicellular development of the fil...
ORGANISM(S): Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) 
2023-08-10 | PXD043205 | Pride
Cop9 signalosome Aspergillus nidulans Gfp-affinity purifications Csn complex Native complex assembly Subcomplexes 
ProteomicsA Mass Spectrometry Approach Reveals a New Toxic Role For Alzheimer’s Disease Aβ Peptide: SPLICEOSOME IMPAIRMENT
Alzheimer’s disease is the most common form of dementia, and its prevalence increases exponentially with age. The patients affected gradually lose cognitive function, control over their sense of orientation, their emotions, and other aspects of behavior. Thirty-five million people are now considered...
ORGANISM(S): Homo sapiens (Human) 
2017-02-06 | PXD002842 | Pride
Aβ42 Alzheimer’s disease Human Orbitrap Splicing Ad early events 
UnknownVanadium pentoxide induces pulmonary inflammation and tumor promotion in a strain-dependent manner.
Not available
S-EPMC2861012 | biostudies-literature
ProteomicsHDX-MS data for VHL Apo/Drug/Ternary states
These open source (.mzxml files) are processed using ExMS (a matlab program, ref 1) and are directly readable. ExMS produces these outfiles (.txt) which are then parsed and fitted using binomial decomposition to determine the number of carried deuterium at a given time point as indicated in the file...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-12-14 | MSV000090905 | MassIVE
UnknownChickens, more than humans, focus the diversity of their immunoglobulin genes on the complementarity-determining region but utilise amino acids, indicative of a more cross-reactive antibody repertoire.
Not available
S-EPMC9772431 | biostudies-literature
UnknownReduced axonal surface expression and phosphoinositide sensitivity in Kv7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy.
Not available
S-EPMC6415549 | biostudies-literature
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