Wang Fengfei F - OmicsDI

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Proteomics (2)
Metabolomics (1)

Organisms

Homo sapiens (2)
Mus musculus (1)

Repository

iProX (1)
MetaboLights (1)
pride (1)

Tissue

Cell culture (1)
Epithelial cell (1)

Disease

Breast cancer (1)

Technology Type

Mass spectrometry (1)
Mass Spectrometry (1)
Shotgun proteomics (1)

Instrument Platform

Q Exactive (1)

Publication Date

2025 (1)
2021 (1)
2018 (1)

CHEBI ID

CHEBI:132188 (1)
CHEBI:132477 (1)
CHEBI:132479 (1)
CHEBI:132948 (1)
CHEBI:132966 (1)
CHEBI:133139 (1)
CHEBI:133141 (1)
CHEBI:133144 (1)
CHEBI:133186 (1)
CHEBI:13332 (1)
CHEBI:133460 (1)
CHEBI:133469 (1)
CHEBI:133515 (1)
CHEBI:133523 (1)
CHEBI:133672 (1)
CHEBI:133677 (1)
CHEBI:133693 (1)
CHEBI:133733 (1)
CHEBI:138368 (1)
CHEBI:138529 (1)
CHEBI:141472 (1)
CHEBI:143243 (1)
CHEBI:145970 (1)
CHEBI:146193 (1)
CHEBI:146206 (1)
CHEBI:15245 (1)
CHEBI:15318 (1)
CHEBI:15346 (1)
CHEBI:15351 (1)
CHEBI:15354 (1)

Metabolite Name

1-(1-enyl-palmitoyl)-2-arachidonoyl-GPC (P-16:0/20:4)* (1)
1-(1-enyl-palmitoyl)-2-arachidonoyl-GPE (P-16:0/20:4)* (1)
1-(1-enyl-palmitoyl)-2-linoleoyl-GPC (P-16:0/18:2)* (1)
1-(1-enyl-palmitoyl)-2-linoleoyl-GPE (P-16:0/18:2)* (1)
1-(1-enyl-palmitoyl)-2-palmitoleoyl-GPC (P-16:0/16:1)* (1)
1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0)* (1)
1-(1-enyl-palmitoyl)-GPE (P-16:0)* (1)
1-(1-enyl-stearoyl)-GPE (P-18:0)* (1)
1-arachidonoyl-GPI (20:4)* (1)
1-lignoceroyl-GPC (24:0) (1)
1-linoleoyl-GPC (18:2) (1)
1-methylguanidine (1)
1-methylhistidine (1)
1-methylnicotinamide (1)
1-myristoyl-2-palmitoyl-GPC (14:0/16:0) (1)
1-oleoyl-2-docosahexaenoyl-GPC (18:1/22:6)* (1)
1-oleoyl-2-linoleoyl-GPE (18:1/18:2)* (1)
1-oleoyl-GPI (18:1)* (1)
1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4)* (1)
1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6) (1)
1-palmitoyl-2-docosahexaenoyl-GPE (16:0/22:6)* (1)
1-palmitoyl-2-linoleoyl-GPE (16:0/18:2) (1)
1-palmitoyl-2-oleoyl-GPC (16:0/18:1) (1)
1-palmitoyl-2-palmitoleoyl-GPC (16:0/16:1)* (1)
1-palmitoyl-2-stearoyl-GPC (16:0/18:0) (1)
1-palmitoyl-GPC (16:0) (1)
1-palmitoyl-GPE (16:0) (1)
1-palmitoyl-GPI (16:0) (1)
1-stearoyl-2-arachidonoyl-GPC (18:0/20:4) (1)
1-stearoyl-2-arachidonoyl-GPE (18:0/20:4) (1)

Lab affiliation

UW Madison (1)

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PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis

Metabolic reprogramming is a hallmark of cancer. Herein we discover that the key glycolytic enzyme pyruvate kinase M2 isoform (PKM2), but not the related isoform PKM1, is methylated by co-activator-associated arginine methyltransferase 1 (CARM1). PKM2 methylation reversibly shifts the balance of met...

2021-07-30 | MTBLS533 | MetaboLights

PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis

Global proteome comparison between breast cancer MCF7 parental cell and PKM2 KO cell

ORGANISM(S): Homo sapiens (Human)

2018-10-24 | PXD007671 | Pride

Lc-ms Breast cancer

Lysine-targeting, covalent inhibitors of bromodomain BD1 of BET proteins in live cells and animals

We report herein a set of activity-based probes (ABPs; P3-P7) based on various lysine-reactive covalent warheads capable of global profiling of ligandable lysine within BRDs in live cells and animals. Chemoproteomic experiments with P7 by utilizing 2-ethynylbenzaldehyde (EBA) identified 18 endogenou...

ORGANISM(S): Homo Sapiens Mus Musculus

2025-04-10 | PXD058513 |

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