Sort   by:  
 Page size 
Oncogenic mutations in p110α subunit of phosphatidylinositol-3-kinase (PI3K), primarily H1047R in the kinase domain and E545K in the helical domain, induce constitutive PI3K/AKT pathway activation, driving tumor progression. Isoform-specific inhibitors such as alpelisib have been developed, but thei...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD067648 | Pride
The performance of the S-Trap protocol for phosphoproteomics studies for proteome and phosphoproteome was systematically evaluated in big-scale and small-scale samples. The results showed the existing protocol was problematic for phsophopeptides enrichment. After employing optimized S-Trap methodol...
ORGANISM(S): Homo sapiens (Human) 
2023-06-19 | PXD037751 | Pride
Sort   by:  
 Page size