A hallmark feature of glioblastoma (GBM) cells is its strong self-renewal potential and immature differentiation state -- stem cell-like properties which may contribute to the plasticity and intense therapeutic resistance of GBM. The molecular basis of the immature differentiation profile remains a...
The maintenance of advanced malignancies relies on continued activity of driver oncogenes, although their rate-limiting role is highly context-dependent with respect to tumor types and associated genetic alterations. Oncogenic Kras mutation is the signature event in human pancreatic ductal adenocar...
We conducted a DIA-based proteomics study for 5 patients with CHD-PBS Syndrome, 5 patients with CHD-NPBS Syndrome, and 5 healthy adults to explore the biomarkers of PBS Syndrome.
