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ProteomicsDeep Multilayer Brain Omics Identifies Molecular Networks in Glioma’s Disease Progression
Risk of high grade gliomas is lower in young females and its incidence enhances after menopause suggesting likely protective roles of female hormones. Little is known about risk factors for adult glioma. Menopause hormone changes have received some attention as a possible risk factor.
ORGANISM(S): Mus Musculus 
2021-12-01 | PXD030195 |
UnknownPhotocatalytic streamlined dual-functional group transfer from cyanopyridine to internal alkynes.
Not available
S-EPMC12511331 | biostudies-literature
ProteomicsMultifunctional polyphenol-based silk hydrogel alleviates oxidative stress and enhances endogenous regeneration of osteochondral defects
The native microenvironment following osteochondral defect is not permissive for its endogenous regeneration. A variety of hydrogels have been developed to regulate cell behaviors; however, there is still a lack of hydrogels with multifunctional properties that can provide a supportive microenvironm...
ORGANISM(S): Rattus Rattus 
2021-11-28 | PXD030026 |
ProteomicsAntler stem cell-conditioned medium data independent acquisition
The process of chondrogenesis in deer antlers is very similar to that of mammalian cartilage formation. Antlers can regenerate at an alarming rate (up to 2 cm per day). To meet the rapid growth of antlers, paracrine factors play an important role. These paracrine factors promote the proliferation an...
ORGANISM(S): Cervus elaphus hippelaphus 
2023-04-11 | PXD041259 | Pride
Data independent acquisition Deer，antler stem cell-conditioned medium Antler stem cell 
ProteomicsSerum proteomics identify biomarkers associated with the pathogenesis of idiopathic pulmonary fibrosis
This serum proteomic profile provides rigorous evidence that enables understanding of the heterogeneity of IPF and protein alterations that could help in its diagnosis and treatment decisions.
ORGANISM(S): Homo Sapiens 
2024-05-16 | PXD052329 |
ProteomicsHuman T21 Amniocyte samples LC-MS/MS
Amniocyte samples of T21 males, T21 females, CN males, and CN females were collected by amniocentesis. The quantitative value of the peptide corresponding to each sample was determined through quantitative analysis by mass spectrometry.
ORGANISM(S): Homo Sapiens 
2022-03-31 | PXD032883 |
ProteomicsHuman milk protein components assessed by proteome analysis on a fast and robust micro-flow LC‒MS/MS system
Human milk is considered the best food for infants and young children, and an in-depth exploration of its molecular composition could provide a scientific basis for the development and production of substitutes. Therefore, we developed a micro-flow liquid chromatography tandem mass spectrometry (μLC...
ORGANISM(S): Homo Sapiens 
2026-02-10 | PXD074321 |
ProteomicsSilk-based hydrogel incorporated with metal-organic framework nanozymes for enhanced osteochondral regeneration
Osteochondral defects (OCD) cannot be efficiently repaired due to the unique physical architecture and the pathological microenvironment including enhanced oxidative stress and inflammation. Conventional strategies, such as the control of implant microstructure or the introduction of growth factors,...
ORGANISM(S): Rattus Norvegicus Mus Musculus 
2022-03-04 | PXD031852 |
ProteomicsMechanisms underlying Florfenicol-induced stem cell toxicity using iTRAQ
iTRAQ-based proteomics was performed to explore the mechanism underlying Florfenicol-induced stem cell toxicity and assess the overall protein changes in P19SCs post FLO treatment.
ORGANISM(S): Mus Musculus 
2021-09-26 | PXD028764 |
ProteomicsDeacetylation Induced Nuclear Condensation of HP1γ Promotes Multiple Myeloma Drug Resistance
Functional crosstalk between histone modifications and chromatin remodeling has emerged as a key regulatory mode of transcriptional control during drug resistance, but the underlying mechanisms are not fully understood. Here we demonstrate that different proteins and their acetylation modification r...
ORGANISM(S): Homo Sapiens 
2023-02-20 | PXD040298 |
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