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TranscriptomicsmiRNAs expression profiling from mouse heart after Ang II (angiotensin II) (1500ng/kg/min) infusion for 3 days and 7 days
Angiotensin II stimulates fibroblast proliferation and substantially alters gene expression patterns leading to cardiac remodeling, but the mechanisms for such differences are unknown. MicroRNAs are a novel mechanism for gene expression regulation. Herein we tested the miRNAs patterns in mouse heart...
ORGANISM(S): Mus musculus 
2015-06-05 | E-GEOD-69559 | biostudies-arrayexpress
Genomicsena-DATASET-LUDJHU-22-08-2017-18:25:45:667-381 - samples
Samples prepared using Safe-SeqS technology. All samples ran on an Illumina MiSeq instrument. Fastq files for read 1 and the index read present (R and I respectively).
EGAD00001003579 | EGA
GenomicsCirculating Tumor DNA Analysis Detects Minimal Residual Disease and Predicts Recurrence in Patients with Stage II Colon Cancer
Detection of circulating tumor DNA (ctDNA) after resection of stage II colon cancer may identify those at the highest risk of recurrence and help inform adjuvant treatment decisions. We used massively-parallel-sequencing–based assays to evaluate the ability of ctDNA to detect minimal residual diseas...
EGAS00001001839 | EGA
Genomicsena-DATASET-LUDJHU-29-01-2018-17:38:21:660-204 - samples
Sequencing data from 1,005 cancer patients and 812 healthy controls. All samples prepared using Safe-SeqS technology and sequenced on an Illumina MiSeq and/or HiSeq instrument. Paired FASTQ files for correspond to read 1 and the index read present (R and I respectively).
EGAD00001003931 | EGA
GenomicsDetection and localization of surgically resectable cancers with a multi-analyte blood test
Earlier detection is key to reducing cancer deaths. Here we describe a blood test that can detect eight common cancer types through assessment of the levels of circulating proteins and mutations in cell-free DNA. We applied this test, called CancerSEEK, to 1,005 patients with clinically detected can...
EGAS00001002764 | EGA
UnknownMTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue.
Not available
S-EPMC12061245 | biostudies-literature
ProteomicsPBRM1-deficient PBAF complexes target de novo genomic loci to activate pro-survival genes in clear cell renal cell carcinoma (PBRM1 dataset)
PBRM1 is lost in 40% of clear cell renal cell carcinomas (ccRCC) and the combined loss of VHL and PBRM1 drives ccRCC tumorigenesis. PBRM1 is an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler and despite its well-established role as a tumor suppressor, we have limited under...
ORGANISM(S): Homo Sapiens (human) 
2021-07-24 | PXD020554 | JPOST Repository
ProteomicsPBRM1-deficient PBAF complexes target de novo genomic loci to activate pro-survival genes in clear cell renal cell carcinoma (BRG1 dataset)
PBRM1 is lost in 40% of clear cell renal cell carcinomas (ccRCC) and the combined loss of VHL and PBRM1 drives ccRCC tumorigenesis. PBRM1 is an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler and despite its well-established role as a tumor suppressor, we have limited under...
ORGANISM(S): Homo Sapiens (human) 
2021-07-24 | PXD020553 | JPOST Repository
UnknownEndovascular treatment for cerebral venous thrombosis: a multicenter study in China.
Not available
S-EPMC11978133 | biostudies-literature
TranscriptomicsGenetic Structure of Duplicated Sequences Revealed by Genotyping Single Sperm
Three different experimental approaches were evaluated for discrimination of genomic variance in and between duplicated sequences using 48 markers in duplicon regions and 17 SNPs in unique sequences previously characterized in another study. We found only the method high-throughput single sperm typi...
ORGANISM(S): Homo sapiens 
2008-07-25 | E-GEOD-11957 | biostudies-arrayexpress
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