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ProteomicsQuantitative proteomics analysis of acute myeloid leukemia cells after NAT10 knockdown
RNA modification represents an important post-transcriptional regulatory mechanism in acute myeloid leukemia (AML). Given that the critical function of ac4C in control RNA translation, we sought to investigate the global impact of ac4C on protein expression. To this end, we conducted tandem mass tag...
ORGANISM(S): Homo sapiens (Human) 
2024-08-26 | PXD055119 | Pride
Rna acetylation (ac4c)  acute myeloid leukemia  leukemic stem cells (lscs)  metabolic reprogramming  serine synthesis pathway  epigenetic inhibitor 
UnknownAlternative splicing analysis of lignocellulose-degrading enzyme genes and enzyme variants in Aspergillus niger.
Not available
S-EPMC11031446 | biostudies-literature
UnknownRibosomal protein L27 contributes to virulence and maduramicin resistance in Eimeria tenella.
Not available
S-EPMC12509730 | biostudies-literature
ProteomicsSpatiotemporal dog brain proteome
The complexity and low accessibility of the human brain make it challenging to understand its development, function, and disorders. Brain diseases including neurodegenerative disease and psychiatric diseases incur huge medical and social burdens without effective treatments. While mouse has substant...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2022-08-12 | PXD033420 | Pride
Brain Multiple regions Proteome Canine 
ProteomicsSpatiotemporal dog brain proteome
The complexity and low accessibility of the human brain make it challenging to understand its development, function, and disorders. Brain diseases including neurodegenerative disease and psychiatric diseases incur huge medical and social burdens without effective treatments. While mouse has substant...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2022-08-12 | PXD034449 | Pride
Brain Multiple regions Proteome Canine 
UnknownStructural and functional characterization of a new thermophilic-like OYE from Aspergillus flavus.
Not available
S-EPMC10787880 | biostudies-literature
UnknownModeling the complete spatiotemporal spread of the COVID-19 epidemic in mainland China.
Not available
S-EPMC8056483 | biostudies-literature
TranscriptomicsSIRT1 negatively regulates the differentiation of IL-9-producing CD4+T cells
Distinct metabolic programs support the differentiation of CD4+T cells into their separate lineages. In this study, we investigated metabolic mechanisms underlying the differentiation of IL-9 producing-CD4+T cells (TH9) in allergic airway inflammation and cancerous tumors. We found here that SIRT1 n...
ORGANISM(S): Mus musculus 
2016-06-14 | E-GEOD-79607 | biostudies-arrayexpress
ProteomicsHAX1-interactome in Colorectal Cancer cell line (HCT116)
We performed immune-affinity purification and resolved the binding partners utilizing mass spectrometry to elucidate the molecular mechanism of HAX1-mediated CRC progression. HCT116 cells transfected with empty vector or Flag-HAX1 and then immunoprecipitated using anti-Flag M2 beads. The purified HA...
ORGANISM(S): Homo Sapiens 
2024-01-11 | PXD048485 |
TranscriptomicsMaternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice-the long term restoration
Early-life antibiotic exposure perturbs the intestinal microbiota, alters innate intestinal immunity, and accelerates type 1 diabetes development in the NOD mouse model. Here we found that maternal cecal microbiota transfer (CMT) to NOD mice with early-life antibiotic perturbation partially rescued ...
ORGANISM(S): Mus musculus 
2021-09-02 | E-MTAB-9982 | biostudies-arrayexpress
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