Sort   by:  
 Page size 
Proteomics,MultiomicsCyclin C-CDK3/8/19 kinases play a tumor-suppressive role in vivo
Cyclin C was cloned as a growth-promoting G1 cyclin1,2, and several studies postulated a role for cyclin C in driving cell proliferation3-8 . Moreover, cyclin C, together with its kinase partner, the cyclin-dependent kinase CDK8, is believed to represent an essential component of basal transcrip...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080728 | MassIVE
ProteomicsA ubiquitin-based effector-to-inhibitor switch coordinates brain, craniofacial, and skin development
The molecular mechanisms that coordinate patterning of the embryonic ectoderm into spatially distinct lineages to form the nervous system, epidermis, and craniofacial structures are unclear. Here, biochemical disease-variant profiling reveals a posttranslational pathway that drives early ectodermal ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-14 | MSV000090711 | MassIVE
UnknownSugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations.
Not available
S-EPMC8373451 | biostudies-literature
UnknownInteraction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
Not available
S-EPMC5260796 | biostudies-literature
UnknownIntravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.
Not available
S-EPMC10600726 | biostudies-literature
GenomicsPOPRES: Population Reference Sample

Technological and scientific advances, stemming in large part from the Human Genome and HapMap projects, have made large-scale, genome-wide investigations feasible and cost-effective. These advances have the potential to dramatically impact drug discovery and development by identifying genet...

phs000145.v2.p2 | EGA
UnknownDerivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells.
Not available
S-EPMC7796997 | biostudies-literature
UnknownAn abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people.
Not available
S-EPMC4319976 | biostudies-literature
UnknownAssociation of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
Not available
S-EPMC3928662 | biostudies-literature
UnknownGenome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent.
Not available
S-EPMC5803424 | biostudies-literature
Sort   by:  
 Page size