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UnknownUnveiling Structural Diversity of Uranyl Compounds of Aprotic 4,4'-Bipyridine N,N'-Dioxide Bearing O-Donors.
As an aprotic O-donor ligand, 4,4'-bipyridine N,N'-dioxide (DPO) shows good potential for the preparation of uranyl coordination compounds. In this work, by regulating reactant compositions and synthesis conditions, diverse coordination assembly between uranyl and DPO under different r...
S-EPMC9996810 | biostudies-literature
UnknownThe PANoptosis-related hippocampal molecular subtypes and key biomarkers in Alzheimer's disease patients.
Alzheimer's Disease (AD) is a neurodegenerative disorder, and various molecules associated with PANoptosis are involved in neuroinflammation and neurodegenerative diseases. This work aims to identify key genes, and characterize PANoptosis-related molecular subtypes in AD. Moreover, we establish a sc...
S-EPMC11470079 | biostudies-literature
UnknownRelationship between body composition and pulmonary function in the general population-a cross-sectional study in Ningxia.
Studies considering the relationship between non-obesity-related body composition and lung function are few; therefore, this study aimed to explore these correlations and effects. This cross-sectional study conducted in rural Qingtongxia City and Pingluo County, Ningxia, China, included 776 particip...
S-EPMC10587154 | biostudies-literature
UnknownTherapeutic effects of dental pulp stem cells on vascular dementia in rat models.
Dental pulp stem cells are a type of adult stem cells with strong proliferative ability and multi-differentiation potential. There are no studies on treatment of vascular dementia with dental pulp stem cells. In the present study, rat models of vascular dementia were established by two-vessel occlus...
S-EPMC8323691 | biostudies-literature
UnknownTherapeutic potential of dental pulp stem cell transplantation in a rat model of Alzheimer's disease.
Dental pulp stem cells are dental pulp-derived mesenchymal stem cells that originate from the neural crest. They exhibit greater potential for the treatment of nervous system diseases than other types of stem cells because of their neurogenic differentiation capability and their ability to secrete m...
S-EPMC8178760 | biostudies-literature
UnknownModel Based Identification of Linezolid Exposure-toxicity Thresholds in Hospitalized Patients.
Evidence supports linezolid therapeutic drug monitoring as the exposure-response relationship has been identified for toxicity among patients receiving linezolid, but the data to establish the upper limit are limited and the published toxicity thresholds range widely. The purpose of this study was t...
S-EPMC8525462 | biostudies-literature
GenomicsGenome wide association study of leprosy in Chinese population

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). Due to M. leprae's narrow host range and an inability to be cultured in vitro, the biological investigation of this disease has been difficult. Host genetic factors have been ...

phs000217.v1.p1 | EGA
UnknownEffect of SARS-CoV-2 Breakthrough Infection on HIV Reservoirs and T-Cell Immune Recovery in 3-Dose Vaccinated People Living with HIV.
People living with human immunodeficiency virus (PLWH) are a vulnerable population with a higher risk of severe coronavirus disease 2019 (COVID-19); therefore, vaccination is recommended as a priority. Data on viral reservoirs and immunologic outcomes for PLWH breakthrough infected with severe acute...
S-EPMC10748120 | biostudies-literature
UnknownComplete genome sequence of the bacterium Ketogulonicigenium vulgare Y25.
Ketogulonicigenium vulgare is characterized by the efficient production of 2KGA from L-sorbose. Ketogulonicigenium vulgare Y25 is known as a 2-keto-L-gulonic acid-producing strain in the vitamin C industry. Here we report the finished, annotated genome sequence of Ketogulonicigenium vulgare Y25.
S-EPMC3019938 | biostudies-literature
UnknownTaPPR13, a Pentatricopeptide Repeat Protein Gene Activated by TaBZR2, Confers Drought Stress Tolerance by Enhancing the Antioxidant Defense System and Promoting Retrograde Signaling in Wheat (Triticum aestivum).
The wheat (Triticum aestivum) brassinazole-resistant 2 (TaBZR2) gene is identified as significantly associated with drought tolerance by genome-wide association study (GWAS), and a chloroplast pentatricopeptide repeat (PPR) protein gene TaPPR13 functioned as a positive drought stress regulator downs...
S-EPMC12462999 | biostudies-literature
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