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MetabolomicsMetabolomic characterization of pitaya fruit from three red-skinned cultivars with different pulp colors
Pitaya is a new fruit crop, whose exotically colored fruits have excellent nutritional and antioxidant properties. In this study, the primary metabolite profiles of three pitaya cultivars i.e. 'Guanhuahong' (red peel with red pulp), 'Guanhuabai' (red peel with white pulp) and 'Guanhuahongfen' (red p...
2023-04-04 | MTBLS3860 | MetaboLights
UnknownM<sup>6</sup>A -mediated lncRNA SCIRT stability promotes NSCLC progression through binding to SFPQ and activating the PI3K/Akt pathway.
Not available
S-EPMC11772919 | biostudies-literature
UnknownUBR5 targets tumor suppressor CDC73 proteolytically to promote aggressive breast cancer.
Not available
S-EPMC9098409 | biostudies-literature
UnknownA pharmacological probe identifies cystathionine β-synthase as a new negative regulator for ferroptosis.
Not available
S-EPMC6158189 | biostudies-literature
ProteomicsPeste des petits ruminants virus nucleocapsid protein interacts with PACT and induces stress granule to promote viral replication
Stress granules (SGs) formation is a conserved cellular strategy to reduce stress-related damage regulating cell survival. A Mass spectrometry-based profiling of the interactome of PPRV N protein revealed that PPRV N interacted with PACT to regulate the assembly of SGs. N protein inhibited the inter...
ORGANISM(S): Homo Sapiens 
2022-12-27 | PXD039104 |
ProteomicsThe LC-MS/MS data of EVs derived from Talaromyces marneffei
Our experiment showed that the immunostimulatory effect of EVs derived from Talaromyces marneffei(TM) was significantly weaken with protease pretreatment, but not in pretreatment with dsDNA and RNase A hydrolase. To further investigate its protein composition, EVs derived from TM were further analyz...
ORGANISM(S): Talaromyces Marneffei 
2020-10-26 | PXD022162 |
ProteomicsClinical features and Multiomics Profiles Indicate Coagulation and Platelet Dysfunction as Key Pathological Pathways in COVID-19 Viral Sepsis
Background: The role of viral infections as a mediator of systemic immune dysfunction leading to sepsis has received limited attention compared to the bacterial pathogens. The COVID-19 pandemic and the increased cases of sepsis in the absence of known bacterial pathogens have highlighted the clinica...
ORGANISM(S): Homo Sapiens 
2024-03-03 | PXD050303 |
MetabolomicsSensing Ceramides by CYSLTR2 and P2RY6 to Aggravate Atherosclerosis

Recent evidence shows elevated circulating long-chain ceramide levels predicts atherosclerotic cardiovascular disease (ASCVD) independently of cholesterol. Although targeting ceramides signaling may provide therapeutic benefits beyond the treatment of hypercholesterolemia, the underlying mechanis...

2025-04-15 | MTBLS11925 | MetaboLights
ProteomicsProteomics analysis of the myocardium form chronic hypobaric hypoxia-induced mice model
C57BL/6J mice were assigned to the hypobaric hypoxia chamber for simulation of high-altitude conditions. iTRAQ proteomics analysis/nanoUHPLC-MS/MS analysis was performed accordingly in the right myocardium of mice that had been allowed to develop hypoxia-induced pulmonary hypertension after hypobari...
ORGANISM(S): Mus Sp. 
2023-02-23 | PXD040342 |
ProteomicsCRISPR-Assisted Detection of RNA-Protein Interactions in Living Cells
We develop a CRISPR-Assisted RNA-Protein Interaction Detection method (CARPID), which leverages CRISPR/CasRx-based RNA targeting and proximity labeling to identify binding proteins of specific lncRNA in the native cellular context.
ORGANISM(S): Homo Sapiens 
PXD015702 |
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