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MetabolomicsProduction of chain-extended cinnamoyl compounds by overexpressing two adjacent cluster-situated LuxR regulators in Streptomyces globisporus C-1027

Natural products from microorganisms are important sources for drug discovery. With the development of high-throughput sequencing technology and bioinformatics, a large amount of uncharacterized biosynthetic gene clusters (BGCs) in microorganisms have been found, which show the potential for nove...

2023-09-06 | MTBLS5152 | MetaboLights
UnknownStabilization of a molecular water oxidation catalyst on a dye-sensitized photoanode by a pyridyl anchor.
Not available
S-EPMC7490713 | biostudies-literature
UnknownDual blockades of TIM-3 and PD-1 effectively prevent hyper-progression and enhance the efficacy of anti-PD-1 therapy in high-grade serous ovarian cancer.
Not available
S-EPMC12663596 | biostudies-literature
UnknownAlgM4: A New Salt-Activated Alginate Lyase of the PL7 Family with Endolytic Activity.
Not available
S-EPMC5923407 | biostudies-literature
UnknownmiR-23b is a negative regulator of tumor suppressing PTPRG in colorectal cancer.
Not available
S-EPMC12240168 | biostudies-literature
ProteomicsIsobaric tags for relative and absolute quantitation labeling coupled with 2D-LC MS/MS proteomics analysis of anterior insula in morphine induced place preference rats with high frequency deep brain stimulation intervention
The rats were implanted bilaterally with electrodes in anterior insula and then trained to morphine conditioned place preference and chronic high frequency electrical stimulation was applied during the withdrawal phase. Proteomics analysis of the rat anterior insula was performed using isobaric tags...
ORGANISM(S): Rattus Rattus 
PXD021122 |
UnknownGeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model.
Not available
S-EPMC11615217 | biostudies-literature
ProteomicsProteomics of obstructed kidneys from patients with obstructive nephropathy and unilateral ureteral obstruction mice
Here, we performed proteomics of kidneys obtained from patients with obstructive nephropathy and healthy controls (n=11/8), or from unilateral ureteral obstruction (UUO) mice and sham mice (n=6/6). Proteomic measurement of all human kidney samples resulted in a total of 6089 proteins with an average...
ORGANISM(S): Homo Sapiens Mus Musculus 
2023-01-08 | PXD039314 |
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