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The exact positions of nucleosomes along genomic DNA can influence many aspects of chromosome function, yet existing methods for mapping nucleosomes do not provide the necessary single base pair accuracy to determine these positions. Here we develop and apply a new approach for direct mapping of nuc...
ORGANISM(S): Saccharomyces cerevisiae 
Four male SHR/Ola, BN and SHR-18 rats were fed a normal diet and sacrificed at 9 weeks of age. Four male SHR/Ola and SHR-18 rats at 8 weeks of age were fed 1% NaCl for one week and then sacrificed. Kidneys were removed and frozen in liquid nitrogen for all 20 animals. Total RNA was isolated, labelle...
ORGANISM(S): Rattus norvegicus 
Knowing the exact positions of nucleosomes not only advances our understanding of their role in gene regulation, but also the mechanisms that underlie between-species variation in chromatin structure. We have generated a chemical map of nucleosomes in vivo in Schizosaccharomyces pombe at base pair r...
ORGANISM(S): Schizosaccharomyces pombe 
Peritoneal macrophages from healthy New Zealand White rabbits were treated with exosomes from Cysticercus pisiforms and treated with PBS were used as control.
ORGANISM(S): Oryctolagus Cuniculus 
Two bacterial strains isolated from Chinese oilfield, Dietzia sp. DQ12-45-1b and P. stutzeri SLG510A3-8, were found having synergistic effect on hydrocarbon biodegradation. To investigate the synergy mechanism between the two strains, they were cultivated separately or individually in a two-chamber ...
ORGANISM(S): Dietzia Sp. Dq12-45-1b Pseudomonas Stutzeri 
2019-12-15 | PXD016754 |
We performed proteomics analysis on Lmna-/- hearts from mice at 2 weeks and 1 month of age to investigate the underlying mechanism by which LMNA deletion evokes DCM
ORGANISM(S): Mus Musculus 
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