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UnknownMicroglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Alzheimer's disease therapy.
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S-EPMC12583606 | biostudies-literature
ProteomicsMulti-Omic Serum Analysis Reveals ferroptosis Pathways and Diagnostic Molecular Signatures Associated with Moyamoya Diseases
Moyamoya disease (MMD) is a rare cerebrovascular disease in humans. Although early revascularization can improve symptoms, it cannot reverse the progression of the disease. The current diagnosis still relies on traditional a Digital Subtraction Angiography (DSA) examination, which is invasive and ex...
ORGANISM(S): Homo Sapiens 
2025-04-23 | PXD063258 |
ProteomicsThe presence of HearNPV P26 in hemolymph from the virus-infected insect via liquid chromatography tandem mass spectrometry analysis
To examine whether P26 is involved in the extracellular melanization pathway, we used HearNPV and cotton bollworm as a testing system and detected the presence of HearNPV P26 in hemolymph from the virus-infected insect via liquid chromatography tandem mass spectrometry analysis. P26 was one of the m...
ORGANISM(S): Helicoverpa Armigera Nucleopolyhedrovirus G4 
2022-10-28 | PXD037784 |
ProteomicsSARS-CoV-2-Infected hiPSC-Derived Cardiomyocytes Reveal Dynamic Changes in the COVID-19 Hearts
The ongoing coronavirus disease 2019 (COVID-19) pandemic has had an enormous impact on our societies. Moreover, the disease’s extensive and sustained symptoms are now becoming a nonnegligible medical challenge. In this respect, data show that heart failure is one of the most common readmission diagn...
ORGANISM(S): Homo Sapiens 
2023-12-01 | PXD047427 |
ProteomicsComprehensive Serum Proteomic and Metabolomic Profiles of Pediatric Patients with Moyamoya Disease Reveal Core Pathways
Background: Moyamoya disease (MMD) signifies a cerebrovascular disorder with obscure origin and a more rapid and severe progression in children than adults. This investigation aims to uncover age-associated distinctions through proteomic and metabolomic profiling to gain insights into the underlying...
ORGANISM(S): Homo Sapiens 
2025-04-24 | PXD063265 |
ProteomicsFTO deficiency in older livers exacerbates ferroptosis during ischaemia/reperfusion injury by upregulating ACSL4 and TFRC
Older livers are more prone to hepatic ischaemia/reperfusion injury (HIRI), which severely limits their utilization in liver transplantation (LT); however, the potential mechanism remains unclear. Here, we demonstrated older livers exhibit a higher degree of ferroptosis during HIRI. Inhibiting ferro...
ORGANISM(S): Mus Musculus 
2024-04-12 | PXD051387 |
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