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MetabolomicsMetabolomic Profiling of the Striatum in Shank3 Knockout ASD Rats: Effects of Early Swimming Regulation

OBJECTIVE: This study aimed to investigate the regulatory impact of early swimming intervention on striatal metabolism in Shank3 gene knockout ASD model rats.

METHODS: Shank3 gene knockout exon 11-21 male 8-day-old SD rats were used as experimental subject...

2024-09-27 | MTBLS8577 | MetaboLights
ProteomicsQuantitative analysis of acetylation in Vero cells infected with Peste des petits ruminants virus
Peste des petits ruminants virus (PPRV) is a negative-stranded RNA virus belonging to the Paramyxoviridae family and causes acute, highly contagious disease in small ruminants. Lysine acetylation plays central role in regulating gene expression. However, the extent and function of lysine acetylation...
ORGANISM(S): Chlorocebus sabaeus 
2023-10-24 | PXD025081 | Pride
Post-translational modification lysine acetylation  protein-protein interaction peste des petits ruminants virus 
ProteomicsThe proteomics analysis of Crassostrea gigas under Zn and Cd contamination
Understanding organisms’ environmental adaptation mechanisms is a fundamental question in ecology and evolution. The oyster Crassostrea gigas is able to accumulate high levels of zinc (Zn) and cadmium (Cd) without self-poisoning, and is thus widely used for pollution detection. However, the molecula...
ORGANISM(S): Crassostrea gigas (Pacific oyster) (Crassostrea angulata) 
2018-10-25 | PXD003290 | Pride
Proteomics Crassostrea Ecotoxicology Heavy-metal 
ProteomicsSystematic Analysis of Lysine Succinylation in Vero cell infected with small ruminant morbillivirus
Small ruminant morbillivirus (SRMV), formerly named Peste-des-petits ruminanats virus (PPRV), belongs to the genus Morbillivirus genus in the family Paramyxoviridae and leads to a highly contagious disease in small ruminants, especially goats and sheep. Lysine succinylation is a newly identified and...
ORGANISM(S): Chlorocebus sabaeus 
2025-05-06 | PXD025025 | Pride
Post-translational modification  lysine succinylation  protein-protein interaction  small ruminant morbillivirus 
ProteomicsSpiroplasma eriocheiris restricts Eriocheir sinensis Wnt signaling pathway to promote pothogen infection and cause host tremor
Spiroplasma eriocheiris, has been identified as a novel lethal pathogen of Eriocheir sinensis tremor disease (TD), one neurological disease with typically paroxysmal tremors of the pereiopod. This pathogen infected and multiplied in the hemocytes of E. sinensis as the first target cells, and then fo...
ORGANISM(S): Eriocheir sinensis (Chinese mitten crab) 
2025-10-06 | PXD022892 | Pride
Wnt signaling pathway  eriocheir sinensis  spiroplasma eriocheiris  tremor disease  thoracic ganglion 
ProteomicsHuman cholangiocarcinoma LC-MS/MS
The glycosylation landscape of Human cholangiocarcinoma (CCA), and how it affects CCA diagnosis and prognosis, has recently emerged as an appealing research field.In this study, we used chemical glycoproteomic analysis Click-iG for systematic profiling of intact glycopeptides in CCA and HIBEpiC cell...
ORGANISM(S): Homo sapiens (Human) 
2024-06-22 | PXD048188 | Pride
Glycoproteomics Click-ig Cholangiocarcinoma 
TranscriptomicsGene expression profiles of hepatocyte-like cells derived from induced pluripotent stem cells (iPSCs) from donors with the Zellweger spectrum of peroxisome biogenesis disorders (PBD-ZSD) and healthy controls
Skin fibroblasts from individuals with PBD-ZSD, a rare autosomal recessive disorder caused by peroxisome assembly defects, show defects in lipid metabolism that provide the basis for clinical diagnostic tests, but are not among the cell types most affected by disease. To explore phenotypes of more c...
ORGANISM(S): Homo sapiens 
2015-05-21 | E-GEOD-69066 | biostudies-arrayexpress
ProteomicsInterplay between acetylation and ubiquitination of Isw1 confers multidrug resistance in Cryptococcus neoformans
Lysine acetylation and ubiquitination are one of many protein modifications and play a crucial role in the biological regulation of many organisms, but little is known about the relationship between acetylation and ubiquitination few. Here, the Isw1 protein is an important member of the chromatin re...
ORGANISM(S): Candida albicans (Yeast) 
2022-12-26 | PXD037150 | Pride
Acetylation  ubiquitination  multidrug resistance 
ProteomicsInfluence of polysaccharides from Polygonatum kingianum on short-chain fatty acid production and quorum sensing in Lactobacillus faecis
Set the bacteria solution without polysaccharides from Polygonatum kingianum(PS) as the control group (CON group), and the bacteria solution with PS added as the administration group (PS group), the target strain treated with and without PS (20 μg/mL) was used for proteomic analysis.
ORGANISM(S): Lactobacillus sp. Y10 
2022-02-16 | PXD029210 | Pride
Lactobacillus faecis 
MetabolomicsExploring the Influence of Psychological Factors on the Comorbidity of Dental Caries and Obesity in Adolescents from the Perspective of the Oral-Gut-Brain Axis

This study explores the impact of psychological factors on the comorbidity of dental caries and obesity in adolescents through the oral-gut-brain axis. An epidemiological survey was conducted on 1,024 students from Beizhen No. 1 Junior High School, with 90 adolescents aged 12–15 included in biosa...

2025-08-22 | MTBLS12873 | MetaboLights
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