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MetabolomicsStage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis

OBJECTIVE: Rheumatoid arthritis (RA) is a progressive disease including four stages, where gut microbiome is associated with pathogenesis. We aimed to investigate stage-specific roles of microbial dysbiosis and metabolic disorders in RA.

METHODS: We investi...

2023-01-31 | MTBLS5297 | MetaboLights
UnknownDevelopment and validation of a radiomics-based nomogram for the preoperative prediction of microsatellite instability in colorectal cancer.
Not available
S-EPMC9087961 | biostudies-literature
TranscriptomicsGenome-wide transcriptome analysis of two maize inbred lines under drought stress during the seedling stage
To understand the transcriptome changes during drought tolerance in maize, the drought-tolerant line Han21 and drought-sensitive line Ye478, which show substantial differences in drought tolerance at the seedling stage, were selected for this study. Using the GeneChip Maize Genome Arrays, we applied...
ORGANISM(S): Zea mays 
2010-06-16 | E-GEOD-16567 | biostudies-arrayexpress
ProteomicsPhosphorylated 4D-Label-free quantitative proteome
The quantitative phosphoprotemic of pad4-1 and bon123pad4-1 before and after Brassinosteroids treatment
ORGANISM(S): Arabidopsis Thaliana 
2024-02-12 | PXD038831 |
MetabolomicsArtificial fermentation with trichome exudate improves microbial community composition and leaf quality in cigar tobacco
Diterpenoids and sucrose esters are synthesized in cigar tobacco leave (CTLs) trichomes and secreted onto leaf surface as trichome exudate (TE), contributing to sensory quality.To reveal the mechanism by which TE affects CTLs quality, this study employed the half-leaf method, utilizing tobacco extra...
2026-06-17 | MTBLS14776 | MetaboLights
ProteomicsProtein expression of Rhodopseudomonas palustris CGA009 during anaerobic nitrogen fixation or non nitrogen fixation
Rhodopseudomonas palustris CGA009 grown anaerobic in photosynthetic medium (PM) or Nitrogen-fixing medium (NFM)
ORGANISM(S): Rhodopseudomonas Palustris Cga009 
2023-06-01 | PXD042610 |
ProteomicsAmelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
Nonalcoholic fatty liver disease (NAFLD) including its more severe manifestation, nonalcoholic steatohepatitis (NASH), is a global public health challenge. Here, we reveal a role for the deubiquitinating enzyme RPN11 in the development of NAFLD and NASH. Ablation of hepatic RPN11 markedly protected ...
ORGANISM(S): Homo Sapiens Mus Musculus 
2024-06-15 | PXD053163 |
ProteomicsSilk-based hydrogel incorporated with metal-organic framework nanozymes for enhanced osteochondral regeneration
Osteochondral defects (OCD) cannot be efficiently repaired due to the unique physical architecture and the pathological microenvironment including enhanced oxidative stress and inflammation. Conventional strategies, such as the control of implant microstructure or the introduction of growth factors,...
ORGANISM(S): Rattus Norvegicus Mus Musculus 
2022-03-04 | PXD031852 |
ProteomicsProteomic profiling and tumor microenvironment characterization reveal molecular and immunological hallmarks of left-sided and right-sided colon cancer tumorigenesis
The protein landscapes of LSCC and RSCC were constructed, and the hallmarks of tumorigenesis and characteristics of TME for LSCC and RSCC were identified. These findings improved our understanding of LSCC and RSCC and may facilitate the development of diagnostic or therapeutic targets for LSCC and R...
ORGANISM(S): Homo Sapiens 
2023-06-13 | PXD042962 |
ProteomicsProteome of human and mouse astrocytes and astrocyte-conditioned medium
Proteome of human and mouse astrocytes and astrocyte-conditioned medium
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-02-05 | PXD060495 |
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