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We used the compond 7 developped by Jianwei Chen's group in P. aeruginosa under different concentrations (blank, 8*MIC and 16*MIC). Then we conducted the differential proteomics testing.
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2026-01-17 | PXD069942 | Pride
Using a transcriptomics approach we explored the mechanism(s) of synergy observed between CDKI-73 and fludarabine in primary CLL cells. The cytotoxic effects of CDKI-73 were associated with transcriptional inhibition of cdk9 target genes including MCL1 and XIAP. In contrast, fludarabine induced the ...
ORGANISM(S): Homo sapiens 
We have conducted proteomics of P. aeruginosa with and without compound 7 which was developped by Chen's group.
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2026-01-17 | PXD070105 | Pride
Foxp3+ T-regulatory cells (Tregs) are key to immune homeostasis such that their diminished numbers or function can cause autoimmunity and allograft rejection. Foxp3+ Tregs express histone/protein deacetylases (HDACs) that regulate chromatin remodeling, gene expression and protein function. Pan-HDAC ...
ORGANISM(S): Mus musculus 
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