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MetabolomicsL-fucose and fucoidan alleviate high-salt diet-promoted acute inflammation

Excessive salt intake is a widespread health issue observed in almost every country around the world. A high salt diet (HSD) has a strong correlation with numerous diseases, including hypertension, chronic kidney disease and autoimmune disorders. However, the mechanisms underlying HSD-promotion o...

2024-02-21 | MTBLS9134 | MetaboLights
UnknownThe genome of the golden apple snail Pomacea canaliculata provides insight into stress tolerance and invasive adaptation.
Not available
S-EPMC6129957 | biostudies-literature
MetabolomicsSpermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
In castration-resistant prostate cancer (CRPC), clinical response to androgen receptor (AR) antagonists is limited mainly due to AR-variants expression and restored AR signaling. The metabolite spermine is most abundant in prostate and it decreases as prostate cancer progresses, but its functions re...
2023-10-11 | MTBLS8034 | MetaboLights
MetabolomicsEffects of Trichoderma and Salicylic Acid/Methyl Jasmonate on the Growth, Development, and Lipid Metabolism of Codonopsis pilosula

Endophytic fungi and phytohormone signaling can jointly influence growth–defense trade-offs in medicinal plants by reprogramming metabolism in a stage-dependent manner. To elucidate how the endophytic fungus Trichoderma longibrachiatum FG and exogenous salicylic acid (SA) and methyl jasmonat...

2026-03-24 | MTBLS14124 | MetaboLights
TranscriptomicsS.japonicum Digital Gene Expression
Schistosoma japonicum is one of the remarkable platyhelminths that are endemic in the South Asian countries. The parasite is dioecious and can parasitize inside host blood stream for many years. Rapid reproduction by producing large number of eggs and count-react or active manipulating host anti-par...
ORGANISM(S): Schistosoma japonicum 
2011-12-01 | E-GEOD-26845 | biostudies-arrayexpress
ProteomicsCollected plasma samples from 30 healthy postpartum women and 30 postpartum depression patients for proteomic analysis using Data-Independent Acquisition (DIA)
Collected plasma samples from 30 healthy postpartum women and 30 postpartum depression patients, performed protein profiling analysis using Data-Independent Acquisition (DIA). Identified differential proteins, conducted functional enrichment analysis, established a diagnostic model for postpartum de...
ORGANISM(S): Homo Sapiens 
2024-03-21 | PXD050851 |
UnknownGenome sequence of the agarwood tree Aquilaria sinensis (Lour.) Spreng: the first chromosome-level draft genome in the Thymelaeceae family.
Not available
S-EPMC7050300 | biostudies-literature
UnknownOlanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress.
Not available
S-EPMC11270788 | biostudies-literature
ProteomicsProteomic analysis of bone marrow cells from wild-type and Dcaf8 knockout mice
To explore the mechanisms by which DCAF8 deficiency induces functional defects in hematopoietic stem cells with an aging-like phenotype, and given DCAF8’s role as a substrate receptor in the E3 ubiquitin ligase complex, we conducted ubiquitin proteomic analysis on bone marrow cells from wild-type an...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-04 | PXD056221 | Pride
Dcaf8  bone marrow  aging 
ProteomicsPharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis
Protein tyrosine phosphatase mitochondrial 1 (PTPMT1), is a member of the protein tyrosine phosphatase superfamily localized on the mitochondrial inner membrane, and regulates the biosynthesis of cardiolipin. Given the important position of PTPMT1 in mitochondrial function and metabolism, pharmacolo...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058606 | Pride
Ptpmt1  mitochondria  ferroptosis  tca cycle  hepatocellular carcinoma 
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