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ProteomicsAcetylation Coordinates the Crosstalk between Carbon Metabolism and Ammonium Assimilation
Enteric bacteria use up to 15% of their cellular energy for ammonium assimilation via glutamine synthetase (GS)/glutamate synthase (GOGAT) and glutamate dehydrogenase (GDH), in response to low or high ammonium availability. However, the sensory mechanisms for effective and appropriate coordination b...
ORGANISM(S): Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
2023-06-21 | PXD039658 | Pride
Ammonium assimilation Acetylation Coordination Carbon metabolism 
ProteomicsGlobal lysine crotonylation and 2-hydroxyisobutyrylation in phenotypically different Toxoplasma gondii parasites
Toxoplasma gondii is a unicellular protozoan parasite of the phylum Apicomplexa. The parasite repeatedly goes through a cycle of invasion, division and induction of host cell rupture, which is an obligatory process for proliferation inside warm-blooded animals. It is known that the biology of the pa...
ORGANISM(S): Toxoplasma gondii 
2019-09-09 | PXD014133 | Pride
Metabolism Protein posttranslational modification Toxoplasma gondii Function Crotonylation 2-hydroxyisobutyrylation 
UnknownRGF Gene Family Analysis and Functional Evidence for RGF8-Mediated Salt Stress Tolerance in Brassica Species.
Not available
S-EPMC11939866 | biostudies-literature
TranscriptomicsS.japonicum Digital Gene Expression
Schistosoma japonicum is one of the remarkable platyhelminths that are endemic in the South Asian countries. The parasite is dioecious and can parasitize inside host blood stream for many years. Rapid reproduction by producing large number of eggs and count-react or active manipulating host anti-par...
ORGANISM(S): Schistosoma japonicum 
2011-12-01 | E-GEOD-26845 | biostudies-arrayexpress
ProteomicsDynamic protein modification of the malaria parasite Plasmodium falciparum and the infected erythrocytes
Plasmodium falciparum, a lethal protozoan, undergoes a complex extra- and intraerythrocytic development cycle that requires intricate and flexible regulatory mechanisms in order to facilitate reproduction and maintain the parasite’s resistance to environmental stress. Protein post-translational modi...
ORGANISM(S): Homo sapiens (Human) Plasmodium falciparum 
2020-11-09 | PXD017503 | Pride
Plasmodium falciparum  infected erythrocytes  intraerythrocytic development cycle  dynamic epigenetics  phosphorylation  acetylation  crotonylation  2-hydroxyisobutyrylation  n-glycosylation  ubiquitination. 
TranscriptomicsGlobal gene expression analysis of the zoonotic parasite Trichinella spiralis revealed novel genes in host parasite interaction
Trichinellosis of human and other mammals was caused through the ingestion of the parasiteM-oM-
ORGANISM(S): Trichinella spiralis 
2013-06-18 | E-GEOD-39151 | biostudies-arrayexpress
ProteomicsLandscapes of post-translational modifications in Trypanosoma parasites
Proteins of all living cells undergo a myriad of posttranslational modifications (PTMs) that are critical to multifarious life processes. In this study, we describe the first comprehensive multiple PTM-omics atlas in parallel with quantitative proteome analyses of two representative species of trypa...
ORGANISM(S): Trypanosoma brucei brucei 
2020-06-30 | PXD016425 | Pride
Trypanosoma brucei  trypanosoma evansi  post-translational modification  acetylation  crotonyltion  2-hydroxyisobutyrylation  malonylation  succinylation  ubiquitination  trimethylation  phosphorylation  n-glycosylation  o-glcnacylation 
ProteomicsComparative Proteomics Analysis of Tibetan Hulless Barley under Drought Stress via Data-Independent Acquisition Mass Spectrometry
Tibetan hulless barley (Hordeum vulgare L. var. nudum) is one of the primary crops cultivated in the mountains of Tibet suffering from low temperature, high salinity, and drought. Specifically, drought is one of the major abiotic stresses that affect and limit Tibetan barley growth. Thus, it's criti...
ORGANISM(S): Hordeum Vulgare 
PXD015597 |
ProteomicsGlucosidase Alpha Neutral C Promotes Influenza Virus Replication by Inhibiting Proteosome-Dependent Degradation of Hemagglutinin
The H7N9 influenza virus poses a significant threat to human health, and the mechanism by which it infects humans remains incompletely understood. Our investigation has unveiled significant insights into the role of glucosidase alpha, neutral C (ganc) gene in human H7N9 infections. Through whole gen...
ORGANISM(S): Homo Sapiens 
2025-03-10 | PXD061732 |
ProteomicsResistance prediction in HGSOC with NACT using data-independent acquisition proteomics and an ovarian tissue-specific spectral library
We firstly built a high-quality ovarian tissue-specific spectral library containing 130,735 peptides and 10,696 proteins on Orbitrap instruments. Compared to a published pan-human spectral library (DPHL), this spectral library provides 10% more ovary-specific and 3% more ovary-enriched proteins. Thi...
ORGANISM(S): Homo Sapiens 
2023-01-02 | PXD039160 |
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