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TranscriptomicsDownregulation of integrin receptor signalling genes by EBV EBNA 3C
Comparsion of cellular gene expression between a control B lymphoma cell-line (BJAB pz2) stably transfected with an empty vector and a BJAB cell-line stably expressing Epstein-Barr virus EBNA 3C (BJAB E3C-4). These cell lines are described in Wang, F., C. Gregory, C. Sample, M. Rowe, D. Liebowitz, R...
ORGANISM(S): Homo sapiens 
2012-03-13 | E-MEXP-3585 | biostudies-arrayexpress
GenomicsGenentech Colon Cancer Screen
Identifying and understanding changes in cancer genomes is essential for the development of targeted therapeutics. Here we analyse systematically more than 70 pairs of primary human colon tumours by applying next-generation sequencing to characterize their exomes, transcriptomes and copy-number alte...
EGAS00001000288 | EGA
UnknownMicroRNA signatures in chemotherapy resistant esophageal cancer cell lines.
Not available
S-EPMC4209553 | biostudies-literature
ProteomicsSecretome from TXNIP knockout human colorectal cell line (DLD1)
Chemotherapy, the standard of care treatment for cancer patients with advanced disease, has been increasingly recognised to activate host immune responses to produce durable outcomes. Here, in colorectal adenocarcinoma (CRC) we identify oxaliplatin-induced Thioredoxin Interacting Protein (TXNIP), a ...
ORGANISM(S): Homo sapiens (Human) 
2024-08-12 | PXD051666 | Pride
Human Txnip Colorectal Secreted 
TranscriptomicsThe role of Gaq in MLL leukemogenesis
Beta-catenin has a central role for self-renewal of leukemic stem cells in Mixed Lineage Leukemia (MLL)-arranged acute myeloid leukemia (AML), however its upstream modulators that can enhance this pathway remain largely unexplored. Through genome-wide gene expression analysis, we identified a previo...
ORGANISM(S): Mus musculus 
2016-02-25 | E-MTAB-4078 | biostudies-arrayexpress
no omics definedTranscription profiling of two highly salt-tolerant wheat lines, their parental lines, and a salt-sensitive line in salt stress and control growth conditions
Comparative expression analysis between two highly salt-tolerant wheat lines, their parental lines, and a salt-sensitive line. The Chinese Spring (CS) line is salt sensitive. AJDAj5 and PhI are the two parental lines (with Chinese Spring background), and both have some salt-tolerance. W4909 and W491...
ORGANISM(S): Triticum aestivum 
2007-07-26 | E-MEXP-971 | biostudies-arrayexpress
TranscriptomicsClinically Relevant Copy Number Variations Detected in Cerebral Palsy
Cerebral palsy (CP) represents a group of non-progressive clinically heterogeneous disorders that are characterized by motor impairment and early age-of-onset, frequently accompanied by co-morbidities. The cause of CP has historically been attributed to environmental stressors resulting in brain dam...
ORGANISM(S): Homo sapiens 
2015-07-28 | E-GEOD-70374 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of retrovirus PDGFB-induced glioma
We performed gene expression profilings of platelet-derived growth factor subunit B (PDGFB)-induced mouse glioma to compare the differential transcriptome profiles between Ctrl-T tumor cells and Olig2cKO tumor cells. Expression profiling of Ctrl-T and Olig2cKO brain tumor (glioma) cells, normal olig...
ORGANISM(S): Mus musculus 
2016-05-17 | E-GEOD-80087 | biostudies-arrayexpress
GenomicsCTCF Binding Sites by ChIP-seq from ENCODE/University of Washington
This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Richard Sandstrom mailto:sull@u.washington.edu). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). This tra...
ORGANISM(S): Homo sapiens 
2011-06-29 | E-GEOD-30263 | biostudies-arrayexpress
UnknownCD33 Splicing Polymorphism Determines Gemtuzumab Ozogamicin Response in De Novo Acute Myeloid Leukemia: Report From Randomized Phase III Children's Oncology Group Trial AAML0531.
Not available
S-EPMC5549451 | biostudies-literature
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