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MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Murine UPLC-MS/MS assays)

Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease (COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression remains unknown. Here we showed, through a longitudinal analysis on two cohorts involving four UK centers, that basel...

2023-06-12 | MTBLS6894 | MetaboLights
UnknownPreliminary Study on Tracing the Origin and Exploring the Relations between Growing Conditions and Isotopic and Elemental Fingerprints of Organic and Conventional Cavendish Bananas (Musa spp.).
Not available
S-EPMC8151364 | biostudies-literature
UnknownQuantification of oxidative DNA lesions in tissues of Long-Evans Cinnamon rats by capillary high-performance liquid chromatography-tandem mass spectrometry coupled with stable isotope-dilution method.
Not available
S-EPMC3056914 | biostudies-literature
UnknownOptimization of Sources of Circulating Cell-Free DNA Variability for Downstream Molecular Analysis.
Not available
S-EPMC8647427 | biostudies-literature
TranscriptomicsIdentification of genes critical for resistance to infection by West Nile virus using RNA-Seq analysis
Background: West Nile virus is an emerging infection of biodefense concern and there are no available treatments or vaccines. Here we used a high-throughput method based on a novel gene expression analysis, RNA-Seq, to give a global picture of differential gene expression by primary human macrophage...
ORGANISM(S): Homo sapiens 
2014-01-08 | E-GEOD-40718 | biostudies-arrayexpress
TranscriptomicsDistinct classes of genes behave as either drivers or dependents of replication timing switches (Replication-Timing).
Duplication of the genome in mammalian cells occurs in a defined temporal order referred as its replication-timing program (RT). RT is regulated in units of 400-800 Kb referred as replication domains (RDs) and changes dynamically during development. Changes in RT are generally coordinated with trans...
ORGANISM(S): Homo sapiens 
2015-05-28 | E-GEOD-63428 | biostudies-arrayexpress
TranscriptomicsImpaired TLR3-mediated immune responses from macrophages of patients chronically infected with Hepatitis C virus
Hepatitis C virus (HCV) is the most common chronic blood-borne infection in the United States with the majority of patients becoming chronically infected and a subset (20%) progressing to cirrhosis and hepatocellular carcinoma. Individual variations in immune responses may help define successful res...
ORGANISM(S): Homo sapiens 
2013-03-05 | E-GEOD-40812 | biostudies-arrayexpress
UnknownMeta-analysis of ICU Delirium Biomarkers and Their Alignment With the NIA-AA Research Framework.
Not available
S-EPMC8897570 | biostudies-literature
UnknownCuproptosis-related molecular subtypes direct T cell exhaustion phenotypes and therapeutic strategies for patients with lung adenocarcinoma.
Not available
S-EPMC10126426 | biostudies-literature
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