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GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
TranscriptomicsAberrantly microRNA profiling in cancerous hepatocytes versus normal primary hepatocytes
MicroRNAs is a rapidly expanding area expected to change the way in which diseases will be diagnosed, treated and monitored in the future. Hepatocellular carcinoma (HCC) shows a rising incidence with high mortality but lack of effective targeted therapies. We identified the aberrantly expressed miRN...
ORGANISM(S): Homo sapiens 
2010-12-30 | E-GEOD-20077 | biostudies-arrayexpress
ProteomicsNon-invasive lipid panel of MASLD fibrosis transition underscores the role of lipoprotein sulfatides in hepatic immunomodulation
use serum lipids panel to distinguish human fibrosis and non-fibrosis liver
ORGANISM(S): Homo Sapiens 
2024-06-27 | PXD051283 |
TranscriptomicsReprogramming fibroblasts into bi-potential hepatic stem cells by defined factors
Recent studies have demonstrated direct reprogramming of fibroblasts into a range of somatic cell types, but to date stem/progenitor cells have only been reprogrammed for the blood and neuronal lineages. We previously reported generation of induced hepatocyte-like (iHep) cells by transduction of Gat...
ORGANISM(S): Mus musculus 
2013-07-19 | E-GEOD-48486 | biostudies-arrayexpress
UnknownIdentification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups.
Not available
S-EPMC7858632 | biostudies-literature
TranscriptomicsA new genome wide expression array and its application to eQTL mapping, synergy to other platforms
The study of gene expression as an intermediate phenotype in associating genotype to disease is growing rapidly. The success of this approach depends heavily on the availability of accurate, high throughput platforms for assaying expression levels of genome-wide gene sets. We evaluated a new platfor...
ORGANISM(S): Homo sapiens 
2012-04-29 | E-GEOD-15905 | biostudies-arrayexpress
UnknownAssociation analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
Not available
S-EPMC6568012 | biostudies-literature
UnknownA meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.
Not available
S-EPMC4383163 | biostudies-literature
UnknownCharacterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.
Not available
S-EPMC10841479 | biostudies-literature
UnknownGermline variation at 8q24 and prostate cancer risk in men of European ancestry.
Not available
S-EPMC6218483 | biostudies-literature
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