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ProteomicsA Tissue-Specific Atlas of Mouse N-Glycoproteome
In this study, we employed StrucGP to generate the first high-resolution and site-specific N- glycoproteomic atlas across 24 diverse mouse tissues. This comprehensive dataset provides an unprecedented insight into the tissue-specific landscape of N-glycosylation, revealing how distinct glycan struct...
ORGANISM(S): Mus Musculus 
2025-05-07 | PXD063701 |
ProteomicsSite-specific N-glycoproteomics of aging mouse uterus tissues for benchmarking the StrucGAP analysis platform
This project presents the site-specific N-glycoproteomics dataset of aging mouse uterus tissues used to demonstrate and validate StrucGAP, a modular and scalable downstream analysis platform for glycoproteomics. Uterine samples were collected from 2- and 12-month-old C57BL/6 female mice (n = 15 per ...
ORGANISM(S): Mus Musculus 
2025-04-23 | PXD063260 |
ProteomicsGlycoproteomic Analyses of Prostate Cancer Cells
Integrated Proteomic and Glycoproteomic Analyses of Prostate Cancer Cells Reveals Glycoprotein Alteration in Protein Abundance and Glycosylation
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080799 | MassIVE
ProteomicsIntegrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Explore This Study at the NCI Proteomic Data Commons

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-28 | MSV000084246 | MassIVE
ProteomicsA comparative study of data-dependent acquisition and data-independent acquisition in proteomics analysis of clinical lung cancer tissues constrained by blood contamination
Proteomics has been used extensively in life mechanism studies, drug target and clinical disease diagnosis, and treatment research.Several clinical surgery tissue samples inevitably get contaminated with blood during cryopreservation. This might detrimentally affect the results obtained by the comm...
ORGANISM(S): Homo Sapiens 
2021-05-10 | PXD025905 |
ProteomicsElevated N-glycosylation of Membrane Proteins Contributes to the Cisplatin Resistance of Non-small-cell Lung Cancer Cells
Chemoresistance remains to be the major restriction on the clinical use of cisplatin. Aberrant changes in protein glycosylation are closely associated with the growth, invasion, metastasis, and resistance to chemotherapy of cancer cells. Comprehensive study on the role of protein glycosylation in th...
ORGANISM(S): Homo Sapiens 
2021-09-18 | PXD028691 |
Proteomicsproteome and phosphoproteome profiling of nonsmall cell lung cancer cells treated by TRAIL
tumor necrosis factor-related apoptosis-inducing liagand is one of the promising cancer therapeutic, however, many tumors have developed different degrees of drug resistance during TRAIL treatment. the mechanism by which is unvlear, and here we reasoned that systematic proteomic and phosphoproteomic...
ORGANISM(S): Homo Sapiens 
2022-06-06 | PXD034338 |
ProteomicsTemporal Proteomic and Lipidomic Profiles of Cerulein-Induced Acute Pancreatitis Reveals Novel Insights for Metabolic Alterations in the Disease Pathogenesis
The pathophysiological mechanisms of acute pancreatitis (AP) are complex and have remained a mystery to date, but metabolism is gradually recognized as an important driver of AP onset and development. We used a cerulein-induced AP mouse model to conduct LC-MS/MS based time-course proteomics and lipi...
ORGANISM(S): Mus Musculus 
2022-12-06 | PXD038567 |
ProteomicsProteomic analysis reveals molecular heterogeneity of adjacent-to-tumor samples in hepatocellular carcinoma
A DIA-MS dataset of 106 samples including 14 healthy liver tissues, 46 pairs of tumor and adjacent-to-tumor samples.
ORGANISM(S): Homo Sapiens 
2022-08-12 | PXD036048 |
ProteomicsThe NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice
To investigate protein expression differences in the ischemic brain between mice treated with vehicle and MLN4924, high-throughput proteomics Liquid Chromatography-Mass Spectrometry (LC-MS)-based analysis was performed.
ORGANISM(S): Mus Musculus 
2021-11-25 | PXD029910 |
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