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Melanoma is the fifth most common newly diagnosed cancer in the U.S., where substitution of valine 600 with glutamic acid (V600E) in BRAF is the most frequently observed mutation in melanoma. Vemurafenib is an FDA-approved kinase inhibitor for BRAFV600E; while the drug can elicit effective remission...
ORGANISM(S): Homo sapiens (Human) 
2025-12-08 | PXD063781 | Pride

BACKGROUND: Pulmonary tuberculosis (TB) and lung cancer (LC) have similar clinical symptoms and atypical imaging findings which are easily misdiagnosed. There is an urgent need for a noninvasive, rapid and accurate biomarker for distinguishing LC from TB.

METHODS:

2024-01-16 | MTBLS6990 | MetaboLights
To analyze the mechanisms underlying DNA-PKcs deletion-mediated renoprotection in an unbiased fashion, we performed proteomic analysis using label free technology to obtain the protein expression profiles in control and DNA-PKcs-deficient mice subjected to septic AKI. 631 proteins were altered by DN...
ORGANISM(S): Acyrthosiphon Pisum 
2021-12-08 | PXD030271 |
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