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MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
MetabolomicsLong-term low-dose ionizing radiation induced chromosome-aberration-specific metabolic phenotype changes in radiation workers

Long-term low-dose ionizing radiation (LLIR) widely exists in human life and has been confirmed to have potential pathogenic effects on cancer and cardiovascular diseases. However, it is technically and ethically unfeasible to explore LLIR-induced phenotypic changes in the human cohort, leading t...

2022-04-07 | MTBLS3854 | MetaboLights
UnknownRisk and prediction of job burnout in responding nurses to public health emergencies.
Not available
S-EPMC10792923 | biostudies-literature
UnknownEndogenous protein S100A14 stabilizes glutaminase to render hepatocellular carcinoma resistant to sorafenib.
Not available
S-EPMC11992768 | biostudies-literature
TranscriptomicsTranscription profiling of mouse epidermal cells sorted into three populations based on alpha 6 integrin, CD34 or Sca-1 surface marker expression
Epidermal keratinocytes were isolated from adult murine skin and FACS sorted into three populations based on their surface maker expression of alpha 6 integrin, CD34 and Sca-1.
- Alpha 6 positive cells constitute the entire population of basal or proliferative keratinocytes from the interfolli...
ORGANISM(S): Mus musculus 
2009-11-16 | E-MEXP-928 | biostudies-arrayexpress
TranscriptomicsUnderstanding the role of Shoc2 protein in spatio-temporal regulation of extracellular signal-regulated kinase (ERK1/2) cascade
This study was designed to understanding changes in RNA transcription in cells depleted of Shoc2 scaffold. 2 samples were analyzed (3 replicates for each sample were included). Cos1 is a control sample.
ORGANISM(S): Chlorocebus sabaeus 
2016-01-15 | E-GEOD-67063 | biostudies-arrayexpress
Proteomicsrat myocardial left ventricular tissue proteins LC-MSMS
Rat left ventricular tissue LC-MSMS.Rat left ventricular tissue proteins from different groups were extracted and quantified using the BCA Protein Assay Kit (Thermo Fisher Scientific, USA). The proteins were then labeled with tandem mass tags (TMT). TMT6/10 (Pierce, USA) with different reporter ions...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-07-26 | PXD024641 | Pride
Rat Heart Lc-msms 
ProteomicsProteomics comparison of protein changes in H1299 cell before and after resistance to cdk4/6 inhibitors
This is the raw proteomics data of H1299 cell before and after resistance to cdk4/6 inhibitors
ORGANISM(S): Homo Sapiens 
2023-05-15 | PXD042216 |
ProteomicsCrf1-FLAG Mass spectrometry-based proteomics data
Mass spectrometry detection of samples co-precipitated with Crf1-FLAG
ORGANISM(S): Pyricularia Oryzae 70-15 
2025-01-19 | PXD059953 |
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