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MetabolomicsOsh2 mediates Candida resistance to miltefosine by regulating zymosterol transport
Miltefosine has been identified for its antifungal properties, yet the mechanisms underlying its action and the development of resistance remain unclear. In this study, we induced drug resistance in various Candida species through concentration gradient exposure, successfully obtaining a miltefosine...
2025-07-03 | MTBLS12270 | MetaboLights
Transcriptomicscis regulated role of lncRNA in transcriptional or developmental process (ChIRP-Seq)
We report that long noncoding RNAs contribute to transcription and developmental process. Thousands of lncRNAs have been identified in the whole genome, and tend to located closely to protein-coding genes. To study position relationship between lncRNA and protein-coding genes, we classified all of l...
ORGANISM(S): Mus musculus 
2016-03-24 | E-GEOD-79541 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of human aortic endothelial cells with lysophosphatidylcholine, IL-35, and IL-10 against controls
Human aortic endothelial cells were stimulated by lysophosphatidylcholine (LPC) (10μM) with or without interleukin 35 (IL-35) (10ng/mL) or IL-10 (10ng/mL) for 18 hours. Total RNAs were extracted from samples, then mRNA and non-coding RNAs were enriched by removing rRNA from the total RNA. The libr...
ORGANISM(S): Homo sapiens 
2019-10-28 | E-MTAB-6604 | biostudies-arrayexpress
UnknownQingxie Fuzheng granules attenuate cancer cachexia by restoring gut microbiota homeostasis and suppressing IL-6/NF-κB signaling in colorectal adenocarcinoma.
Not available
S-EPMC12398093 | biostudies-literature
TranscriptomicsEvx1as and EVX1 knockouts by CRISPR
We report that long noncoding RNAs contribute to transcription and developmental process. Thousands of lncRNAs have been identified in the whole genome, and tend to located closely to protein-coding genes. To study position relationship between lncRNA and protein-coding genes, we classified all of l...
ORGANISM(S): Mus musculus 
2016-03-24 | E-GEOD-70419 | biostudies-arrayexpress
TranscriptomicsFunctional Plasticity of Regulatory T Cell Function
Regulatory T cells (Tregs) can suppress a wide variety of cell types, in diverse organ sites and inflammatory conditions. While Tregs possess multiple suppressive mechanisms, the number required for maximal function is unclear. Furthermore, whether any inter-relationship orcross-regulatory mechani...
ORGANISM(S): Mus musculus 
2011-12-08 | E-GEOD-29262 | biostudies-arrayexpress
ProteomicsTemporal proteomics characterization of COVID-19 patient sera
We enrolled 37 SARS-CoV-2 positive patients including 17 short course (SC) COVID-19 patients (twice viral RNA detection negative over 24 hrs) and 20 COVID-19 long course (LC) COVID-19 patients. We also included 35 SARS-CoV-2 negative patients as control group. We collected 224 inactive serum samples...
ORGANISM(S): Homo Sapiens 
PXD035471 |
ProteomicsProteomic analysis identifies GSN as non-invasive circulating serum biomarker for predicting early recurrence in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is susceptible to early recurrence and lacks effective predictive markers. Mass Spectrometry (MS)-based proteomics has emerged as a potent tool for identifying cancer biomarker profiles in various bodily fluids. In this study, we established a MS-based biomarker discov...
ORGANISM(S): Homo Sapiens 
2023-12-15 | PXD047852 |
Proteomics4E-BP1Ser37 phosphorylation associate with poor prognosis in HCC revealed by quantitative phosphoproteomics of portal vein tumor thrombus
Hepatocellular Carcinoma(HCC)is one of the most common malignat tumor,which is causing the second leading cancer-related death worldwide.
ORGANISM(S): Homo Sapiens 
PXD015570 |
ProteomicsMultiomics analysis revealed proteomic subtyping of hepatocellular carcinoma guide the precise therapy of sorafenib
Multiomics analysis revealed proteomic subtyping of hepatocellular carcinoma guide the precise therapy of sorafenib
ORGANISM(S): Homo Sapiens 
2023-10-30 | PXD046519 |
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