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UnknownMETTL3 Regulates the Inflammatory Response in CPB2 Toxin-Exposed IPEC-J2 Cells through the TLR2/NF-κB Signaling Pathway.
Not available
S-EPMC9781724 | biostudies-literature
ProteomicsTMT labeled Comparative Proteomic Analysis Reveals Active Immune Response during Clostridium perfringens type C Infected Piglet Diarrhea
We performed a TMT labeling-based quantitative spleen proteomic analysis of the control group (SC), tolerance group (SR) and susceptible group (SS) to identify the differentially expressed proteins (DEPs), and screened potential molecular markers of piglet spleen tissues in response to C. perfringen...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-05-20 | PXD030745 | Pride
Tmt labeling  proteome  clostridium perfringens type c  piglet diarrhea  immune response  spleen 
UnknownNPA7: A Dual Receptor Activating Peptide That Inhibits Cardiac Oxidative Stress.
Not available
S-EPMC11839381 | biostudies-literature
MetabolomicsClinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats.

OBJECTIVE: To observe the clinical efficacy and safety of Yiqi Yangxue formula (YQYXF) on knee osteoarthritis (KOA), and to explore the underlying therapeutic mechanism of YQYXF through endogenous differential metabolites and their related metabolic pathways.

METHOD...

2024-03-25 | MTBLS5667 | MetaboLights
UnknownA novel Saclayvirus Acinetobacter baumannii phage genomic analysis and effectiveness in preventing pneumonia.
Not available
S-EPMC11283397 | biostudies-literature
ProteomicsIdentification of regulators of polyploidization presents therapeutic targetsfor treatment of AMKL
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Go...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-27 | MSV000078536 | MassIVE
ProteomicsLactylation of Tau in Human Alzheimers Disease Brain
Aggregation of phosphorylated tau is associated with cognitive impairment in Alzheimers disease patients. In AD a metabolic shift due to the Warburg effect results in increased lactate production. Lactate can induce a post-translational modification on proteins that conjugates lactyl groups to lysin...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000095881 | MassIVE
UnknownThe clinical and immunological features of the post-extracorporeal shock wave lithotripsy anti-glomerular basement membrane disease.
Not available
S-EPMC7808748 | biostudies-literature
TranscriptomicsA global analysis of QTLs for expression variations in rice flag leaf at heading date
Analyses of QTLs for expression levels (eQTLs) of the genes reveal genetic relationship between expression variation and the regulator, thus unlocking the information for identifying the regulatory network. In this study, we used Affymetrix GeneChip Rice Genome Array to analyze eQTLs in rice flag le...
ORGANISM(S): Oryza sativa 
2014-02-05 | E-GEOD-49020 | biostudies-arrayexpress
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
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