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ProteomicsThe protection of Evodiamine against Ulcerative Colitis and Colorectal Cancer via anti-inflammation
Evodiamine (Evo), a kind of alkaloid mostly extracted from Tetradium ruticarpum, which has many pharmacological functions, such as antidiarrheal, antiemetic, and antiulcer effects. In this study, the effects of Evo were investigated in DSS-induced ulcerative colitis (UC) mice and C57BL/6-ApcMinC/Gpt...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD027745 | Pride
Colorectal cancer Inflammation Nf-κb Ulcerative colitis Evodiamine 
ProteomicsBacterial community structure and metabolomic pathways in yak milk and cattle-yak milk during refrigeration: analysis of interspecific differences in dairy spoilage
Raw milk usually needs to be refrigerated at 4℃ before production, and microbial contamination during this process can cause spoilage of refrigerated raw milk. However, there is currently almost no research on plateau characteristic milk (yak milk and cattle-yak milk) (YM and CYM). In this study, si...
ORGANISM(S): Bos Taurus 
2024-03-22 | PXD050886 |
ProteomicsCarnitine palmitoyltransferase 1A promotes mitochondrial fission by enhancing MFF succinylation in ovarian cancer
Mitochondria are dynamic organelles that are important for cell growth and proliferation. Dysregulated mitochondrial dynamics are highly associated with the initiation and progression of various cancers, including ovarian cancer. However, the regulatory mechanism underlying mitochondrial dynamics is...
ORGANISM(S): Homo sapiens (Human) 
2023-05-15 | PXD041990 | Pride
Mitochondrial dynamics  mff  succinylation  ovarian cancer 
TranscriptomicsA genomic atlas of mouse hypothalamic development
The hypothalamus is a central regulator of many behaviors essential for survival such as temperature regulation, food intake and circadian rhythms. However, the molecular pathways that mediate hypothalamic development are largely unknown. To identify genes expressed in developing mouse hypothalamus...
ORGANISM(S): Mus musculus 
2010-05-27 | E-GEOD-21278 | biostudies-arrayexpress
ProteomicsProteomics of Hsc70-interacting Proteins
we compared the interacting proteins between Hsc70-WT and Hsc70-3KA using mass spectrometry to discover additional mediators of this process
ORGANISM(S): Homo Sapiens 
2024-04-05 | PXD051241 |
ProteomicsARIH1 Signaling Promotes Anti-tumor Immunity by Targeting PD-L1 for Proteasomal Degradation
We find EGFR inhibitors promote PD-L1 ubiquitination and proteasomal degradation following GSK3α-mediated phosphorylation of Ser279/Ser283.
ORGANISM(S): Homo Sapiens 
2021-03-01 | PXD024452 |
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