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Proteins are constantly damaged by intracellular and extracellular factors, particularly under stress conditions, leading to an accumulation of modified proteins like isoaspartate (isoD), which is linked to aging and various diseases. The repair enzyme PCMT1 (Protein-L-isoaspartate O-methyltransfera...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-16 | PXD058971 | Pride
We conducted a global quantitative phosphoproteomic and proteomic analysis of left ventricular (LV) tissues from post-infarction chronic heart failure rats. Phosphoproteomic and proteomic analysis can provide insights regarding molecular mechanisms underlying post-infarction chronic heart failure an...
ORGANISM(S): Rattus Norvegicus 
SUG1 associates with multiple transcription factors, such as OsBZR1, OsMADS56 and OsSPL13, to control grain size through GA and BR signaling as well as growth pathways.
ORGANISM(S): Oryza Sativa Japonica Group 
Proteins are the cornerstone of human life, yet the proteomic landscape of aging across human tissues remains largely unexplored. Here, we present a comprehensive proteomic analysis of 520 samples from 15 human tissues, spanning a 50-year lifespan. Our study compiles a proteomic encyclopedia of mult...
ORGANISM(S): Homo Sapiens 
2024-12-06 | PXD058638 |
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