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MetabolomicsFecal metabolomic study in patients with choledocholithiasis concurrent with cholangitis

Metabolites associated with the gut microbiota play an important role in the pathogenesis of choledocholithiasis concurrent with cholangitis (CC). This study aims to characterize the fecal metabolite profile of CC patients and to investigate the correlation and balance within the gut cross-domain...

2025-08-11 | MTBLS12772 | MetaboLights
MetabolomicsSensing Ceramides by CYSLTR2 and P2RY6 to Aggravate Atherosclerosis

Recent evidence shows elevated circulating long-chain ceramide levels predicts atherosclerotic cardiovascular disease (ASCVD) independently of cholesterol. Although targeting ceramides signaling may provide therapeutic benefits beyond the treatment of hypercholesterolemia, the underlying mechanis...

2025-04-15 | MTBLS11925 | MetaboLights
ProteomicsMass spectrometry data of PBMCs after PBS/SEMA3G treatment
The semaphorins encompass a substantial family of secreted and transmembrane glycoproteins, originally recognized as pivotal factors in guiding axonal growth during the development of neural circuitry. Recent studies have uncovered diverse functions of semaphorins in a wide array of immune responses...
ORGANISM(S): Homo Sapiens 
PXD057174 |
ProteomicsProteins raw data using CT-1 in MDA-MB-231
The MDA-MB-231 cells were treated with CT-1 for 24 h. Then the cells were collected for proteomic analysis. SDT buffer was used for sample lysis and protein extraction. Protein digestion by trypsin was performed according to filter-aided sample preparation (FASP) procedure described by Matthias Mann...
ORGANISM(S): Homo Sapiens 
2024-10-30 | PXD057337 |
ProteomicsIdentification of ANXA1 as A Novel Upstream Negative Regulator of Notch1 Function in AML
Abnormal Notch1 expression has an important role in tumorigenesis. However, upstream control mechanisms for Notch1 are still insufficiently understood. Acute myeloid leukemia (AML) is one of the most common and lethal blood malignancies with limited possibilities for treatment. Thus, new therapeutic...
ORGANISM(S): Homo Sapiens 
PXD056593 |
ProteomicsRNA-Pull down and MS for Snhg3
To screen Snhg3-binding proteins using-RNA Pull down and MS
ORGANISM(S): Mus Musculus 
2023-01-17 | PXD039526 |
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