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GenomicsGenome-wide studies identify a novel interplay between AML1 and AML1/ETO in t(8;21) acute myeloid leukemia
The AML1/ETO fusion protein is essential to the development of acute myeloid leukemia (AML), and is well recognized for its dominant-negative effect on the co-existing wild-type protein AML1. However, the involvement of wild-type AML1 in AML1/ETO-driven leukemogenesis remains elusive. Through chroma...
ORGANISM(S): Homo sapiens 
2015-11-04 | E-GEOD-65427 | biostudies-arrayexpress
UnknownT1-2N1M0 triple-negative breast cancer patients from the SEER database showed potential benefit from post-mastectomy radiotherapy.
Not available
S-EPMC6924153 | biostudies-literature
ProteomicsImmunoprecipitates of KDM1A in HepG2 cells with stably overexpressed KDM1A
KDM1A requires an adaptor protein with specific DNA-binding activity to recognize chromatin sequence. We constructed HepG2 cells stably overexpressing KDM1A-Flag tag using lentivirus. We performed Co-IP with Flag-gel and we used LC-MS to determine the immunoprecipitates of KDM1A.
ORGANISM(S): Homo Sapiens 
2023-05-19 | PXD043284 |
ProteomicsProteomic study of exfoliation syndrome
We provided a comprehensive plasma proteome analysis and expanded the profile of human plasma proteome. The differential plasma proteomic analysis of age-related cataract and exfoliation syndrome with/without glaucoma indicated that plasma proteome can reflect the pathophysiological situation of dis...
ORGANISM(S): Homo Sapiens 
2025-03-17 | PXD061945 |
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