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MetabolomicsThe Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis

BACKGROUND: Manchurian walnut (Juglans mandshurica Maxim.) is a tree with multiple industrial uses and medicinal properties in the Juglandaceae family (walnuts and hickories). J. mandshurica produces juglone, which is a toxic allelopathic agent and has potential utilization value...

2022-05-18 | MTBLS3657 | MetaboLights
ProteomicsIdentification of Golgin Imh1 phosphorylation residues under ER stress in yeast
The accumulation of misfolded proteins in the endoplasmic reticulum (ER) induces the unfolded protein response (UPR), which acts through various mechanisms to reduce ER stress. We previously found ER stress induced by tunicamycin (TM) treatment promotes the activation of small GTPase Arl1 and thereb...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-07-21 | PXD031562 | Pride
Snare transport Gtpase arl1 Imh1 Phosphorylation Er stress 
ProteomicsInvestigating the upstream signaling of Imh1 phosphorylation under ER stress in yeast
The accumulation of misfolded proteins in the endoplasmic reticulum (ER) induces the unfolded protein response (UPR), which acts through various mechanisms to reduce ER stress. We previously found ER stress induced by tunicamycin (TM) treatment promotes the activation of small GTPase Arl1 and thereb...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-07-21 | PXD031563 | Pride
Ire1 Snare transport Gtpase arl1 Imh1 Phosphorylation Er stress 
ProteomicsQuantitative proteomics reveals inflammatory signaling in golgin-97 knockout-mediated breast cancer progression
The Golgi apparatus serves as a central hub for trafficking, regulating the anterograde transport and modification of proteins and lipids, or recycling extracellular proteins via retrograde transport through endosomes. Several Golgi-localized proteins have been reported to be involved in regulating ...
ORGANISM(S): Homo sapiens (Human) 
2025-03-07 | PXD056499 | Pride
Breast cancer Golgin-97 Inflammatory Golgi Metastasis 
TranscriptomicsTaxane-selected ovarian cancer cell lines
Each of the six ovarian carcinoma cell lines was exposed to docetaxel or paclitaxel at IC50 levels (the concentration required to kill 50% of the population). After several passages at this initial concentration of taxanes, drug concentrations were escalated, and this process was repeated until vari...
ORGANISM(S): Homo sapiens 
2006-02-24 | E-GEOD-4173 | biostudies-arrayexpress
UnknownRecent Advances in Glycyrrhiza glabra (Licorice)-Containing Herbs Alleviating Radiotherapy- and Chemotherapy-Induced Adverse Reactions in Cancer Treatment.
Not available
S-EPMC9227067 | biostudies-literature
TranscriptomicsTranscription profiling of six ovarian carcinoma cell lines exposed to docetaxel or paclitaxel
Each of the six ovarian carcinoma cell lines was exposed to docetaxel or paclitaxel at IC50 levels (the concentration required to kill 50% of the population). After several passages at this initial concentration of taxanes, drug concentrations were escalated, and this process was repeated until vari...
ORGANISM(S): Homo sapiens 
2006-06-06 | E-SMDB-3612 | biostudies-arrayexpress
UnknownSusceptible gene of stasis-stagnation constitution from genome-wide association study related to cardiovascular disturbance and possible regulated traditional Chinese medicine.
Not available
S-EPMC4501203 | biostudies-literature
TranscriptomicsHost and pathogen interaction: time course [C. albicans]
The interaction between fungal pathogen and host during infection is a complex and dynamic process. To resolve this, we chose the zebrafish model organism as the host to study C. albicans infection via systems biology approach. Transcriptome microarray data and histological analysis of surviving fis...
ORGANISM(S): Candida albicans 
2013-08-26 | E-GEOD-32117 | biostudies-arrayexpress
TranscriptomicsHost and pathogen interaction: time course [zebrafish]
The interaction between fungal pathogen and host during infection is a complex and dynamic process. To resolve this, we chose the zebrafish model organism as the host to study C. albicans infection via systems biology approach. Transcriptome microarray data and histological analysis of surviving fis...
ORGANISM(S): Danio rerio 
2013-08-26 | E-GEOD-32118 | biostudies-arrayexpress
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