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UnknownAlectinib as salvage therapy for metastatic UIMT following misdiagnosis: A case enabling definitive surgery and prolonged remission.
Not available
S-EPMC12666138 | biostudies-literature
MetabolomicsProduction of chain-extended cinnamoyl compounds by overexpressing two adjacent cluster-situated LuxR regulators in Streptomyces globisporus C-1027

Natural products from microorganisms are important sources for drug discovery. With the development of high-throughput sequencing technology and bioinformatics, a large amount of uncharacterized biosynthetic gene clusters (BGCs) in microorganisms have been found, which show the potential for nove...

2023-09-06 | MTBLS5152 | MetaboLights
UnknownSignificant insights from a National survey in China: PrEP awareness, willingness, uptake, and adherence among YMSM students.
Not available
S-EPMC11010336 | biostudies-literature
UnknownDeciphering the chemical profile and pharmacological mechanism of Jinlingzi powder against bile reflux gastritis using ultra-high performance liquid chromatography coupled with Q exactive focus mass spectrometry, network pharmacology, and molecular docking.
Not available
S-EPMC10623248 | biostudies-literature
MetabolomicsSpermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
In castration-resistant prostate cancer (CRPC), clinical response to androgen receptor (AR) antagonists is limited mainly due to AR-variants expression and restored AR signaling. The metabolite spermine is most abundant in prostate and it decreases as prostate cancer progresses, but its functions re...
2023-10-11 | MTBLS8034 | MetaboLights
UnknownHelicobacter pylori SlyD stabilizes TPT1 via hnRNPK and enhances OCT1-mediated CDX2 transcriptional activation to drive gastric intestinal metaplasia.
Not available
S-EPMC11803974 | biostudies-literature
ProteomicsTianlongkechuanling Inhibits Pulmonary Fibrosis Through Down-Regulation Of Arginase-Ornithine Pathway
Background: Pulmonary Fibrosis (PF) is an interstitial lung disease of unknown etiology, characterized by excessive accumulation of extracellular matrix in the lungs, which disrupts the structure and gas exchange of the alveoli. There are only two approved therapies for PF, nintedanib (Nib) and pirf...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD024058 | Pride
Proteomics Pulmonary fibrosis Arginase-ornithine pathway Arginase Tianlongkechuanling 
UnknownIdentification of differential proteomics in Epstein-Barr virus-associated gastric cancer and related functional analysis.
Not available
S-EPMC8274036 | biostudies-literature
UnknownRegulation of CARD8 expression by ANRIL and association of CARD8 single nucleotide polymorphism rs2043211 (p.C10X) with ischemic stroke.
Not available
S-EPMC3962686 | biostudies-literature
ProteomicsProteome and transcriptome analyses reveal key molecular differences between quality parameters of commercial-ripe and tree-ripe fig (Ficus carica L.)
Fig fruit are highly perishable at the tree-ripe (TR) stage. Commercial-ripe (CR) fruit, which are harvested before the TR stage for their postharvest transportability and shelf-life advantage, are inferior to TR fruit in size, color and sugar content. The succulent urn-shaped receptacle serves as t...
ORGANISM(S): Ficus carica 
2019-03-22 | PXD009757 | Pride
Tree ripe Fruit Commercial ripe Proteome 
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