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Paneth cells are defensive cells in the intestinal tract, which secrete niche factors and antimicrobial peptides (AMPs) to maintain the small intestinal stem cell niche and immune homeostasis. Here, we show that Vestigial-like family member 4 (VGLL4) plays a pivotal role in maintaining small intesti...
2026-03-12 | MTBLS10456 | MetaboLights
Reversible HEY1 SUMOylation is a molecular mechanism that coordinates endothelial angiogenic signaling and angiogenesis, both in physiological and pathological milieus, by fine tuning the transcriptional activity of HEY1. Specifically, S UMOylation facilitates the formation of the HEY1 transcription...
ORGANISM(S): Homo Sapiens 
2023-08-18 | PXD044611 |
Immunoprecipitation of OTUD3 interacting proteins was subjected to SDS-PAGE, silver-stained, and identified by mass spectrometry (MS).
ORGANISM(S): Homo Sapiens 
2021-09-26 | PXD028751 |
Macropinocytosis is an effective strategy against nutrient starvation, which fuels cancer cells grow in nutrient-limited conditions. However, whether and how macropinocytosis contributes to the rapid proliferation of hepatocellular carcinoma cells that frequently exhibit inadequate nutrient supply r...
ORGANISM(S): Homo Sapiens 
2022-12-13 | PXD038797 |
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