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UnknownPolymorphisms of glutathione S-transferase genes and survival of resected hepatocellular carcinoma patients.
Not available
S-EPMC4394094 | biostudies-literature
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
ProteomicsVenom proteome of Pachycrepoideus vindemmiae
Parasitoid wasps inject venom containing complex bioactive compounds to regulate the immune response and development of host arthropods and sometime paralyze host arthropods. Although extensive studies have been conducted on the identification of venom proteins in larval parasitoids, relatively few ...
ORGANISM(S): Pachycrepoideus Vindemmiae 
2019-09-27 | PXD015627 |
ProteomicsPhosphoproteomic analysis of EDL muscle
The 5α-DHT-mediated muscle-strengthening effects through the activation of GPR133 were found to be AR-independent. To elucidate the underlying mechanism, we stimulated isolated EDL muscles with 5α-DHT and then performed a phosphoproteomic analysis.
ORGANISM(S): Mus Musculus 
2025-09-08 | PXD057084 |
ProteomicsLow-dose metformin targets the lysosome-AMPK pathway through PEN2
Metformin is the most prescribed anti-diabetic medicine, and has also been shown to have other various benefits, such as anti-aging and anti-cancer effects. For clinical doses of metformin, it is known that AMPK plays a major role; however, the direct molecular target of metformin remains unclear. H...
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-12-01 | PXD030090 |
ProteomicsThe aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
The activity of 5’-adenosine monophosphate-activated protein kinase (AMPK) is inversely correlated with the cellular availability of glucose. When glucose levels are low, the glycolytic enzyme aldolase is not bound to fructose-1,6-bisphosphate (FBP) and, instead, signals to activate lysosomal AMPK. ...
ORGANISM(S): Oryctolagus Cuniculus 
2022-08-10 | PXD035968 |
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