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ProteomicsProteomic and phosphoproteomic data of colorectal cancer tissues and cells for Chromosome-Centric Human Proteome Project
Protein extraction and proteolytic digestion were performed using a Filter-Assisted Sample Preparation (FASP) protocol. In case of phosphopeptide enrichment immobilized Fe(III) affinity chromatography (Fe-IMAC) was performed. The peptides were fractionated using an HPLC system fitted with an SCX col...
ORGANISM(S): Homo sapiens (Human) 
2013-01-11 | PXD000089 | Pride
Phosphopeptides Human colon normal tissues Human colorectal cancer tissues Itraq 
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Cell NAMPTi treatment)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights
TranscriptomicsA new classification of chromosome instability (CIN) phenotype, CIN-high and CIN-low
Samples were taken from colorectal cancers in surgically resected specimens in 35 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be u...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-30540 | biostudies-arrayexpress
TranscriptomicsGene expression signature and the prediction of lymph node metastases
Samples were taken from colorectal cancers in surgically resected specimens in 89 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be u...
ORGANISM(S): Homo sapiens 
2010-08-31 | E-GEOD-4459 | biostudies-arrayexpress
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAD targeted time-course)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7253 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAMPT targeted therapy)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7252 | MetaboLights
TranscriptomicsGene expression signature and the prediction of liver metastasis in colorectal cancer by DNA microarray
Samples were taken from colorectal cancers in surgically resected specimens in 189 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be ...
ORGANISM(S): Homo sapiens 
2011-08-25 | E-GEOD-14095 | biostudies-arrayexpress
ProteomicsHs_HCT116_iTRAQ_HCD
Human colon cancer cell HCT116, iTRAQ labeled, HCD
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe005246 | PeptideAtlas
ProteomicsHs_CRC_phospho_iTRAQ_ITCID
Human colorectal cancer tissue samples, iTRAQ labeled, Phospho enrichemnt, ITCID
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe005293 | PeptideAtlas
ProteomicsHs_HCT116_iTRAQ_ITCID
Human colon cancer cell HCT116, iTRAQ labeled, ITCID
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe005283 | PeptideAtlas
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