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MetabolomicsWhole blood metabolomics of dementia patients reveal classes of disease-linked metabolites

Dementia is caused by factors that damage neurons. We quantified small molecular markers in whole blood of dementia patients, using non-targeted liquid chromatography-mass spectroscopy (LC-MS). Thirty-three metabolites, classified into 5 groups (A-E), differed significantly in dementia patients, ...

2021-07-06 | MTBLS2109 | MetaboLights
UnknownPotential of Z-100, extracted from Mycobacterium tuberculosis strain Aoyama B, as a hot tumor inducer.
Not available
S-EPMC9733245 | biostudies-literature
MetabolomicsMetabolomic Characterization of Knock-Out Mutants in Arabidopsis - Development of a Metabolite Profiling Database for Knock-Out Mutants in Arabidopsis (MeKO)
Despite recent intensive research efforts in functional genomics, the functions of only a limited number of Arabidopsis (Arabidopsis thaliana) genes have been determined experimentally. Thus, improving gene annotation remains a major challenge in plant science. Because metabolite profiling can chara...
2014-03-01 | MTBLS47 | MetaboLights
TranscriptomicsSpatial Transcriptomics of the Epipharynx in Long COVID: Exploring SARS-CoV-2 Signalling Pathways and the Therapeutic Potential of Epipharyngeal Abrasive Therapy
10X VisiumHD spatial transcriptomics of epipharynx from three patients with long COVID and two control individuals without COVID-19.
ORGANISM(S): Homo sapiens 
2025-02-24 | E-MTAB-14669 | biostudies-arrayexpress
ProteomicsHFpEF model heart failure mouse treated with traditional herbal medicine Goreisan
In this project we aimed to investigate the effect of Goreisan (GRS, traditional herbal medicine) on HFpEF model heart failure mouse. HFpEF was induced by administration of high-fat diet (HFD)and N-nitro-L-arginine methyl ester (L-NAME), with or without GRS. Mouse heart proteome was analyzed with LC...
ORGANISM(S): Mus Musculus (mouse) 
2025-09-02 | PXD049259 | JPOST Repository
TranscriptomicsInduced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery
Chronic infantile neurological cutaneous and articular (CINCA) syndrome is an IL-1-driven autoinflammatory disorder caused mainly by NLRP3 mutations. The pathogenesis of CINCA syndrome patients who carry NLRP3 mutations as somatic mosaicism has not been precisely described because of the difficulty ...
ORGANISM(S): Homo sapiens 
2012-06-10 | E-GEOD-38626 | biostudies-arrayexpress
UnknownNational trends in the outcomes of subarachnoid haemorrhage and the prognostic influence of stroke centre capability in Japan: retrospective cohort study.
Not available
S-EPMC10111904 | biostudies-literature
UnknownCommunity-Level Compact City Design, Health Care Provision, and Outcomes of Patients With Stroke.
Not available
S-EPMC12449981 | biostudies-literature
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