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TranscriptomicsA new classification of chromosome instability (CIN) phenotype, CIN-high and CIN-low
Samples were taken from colorectal cancers in surgically resected specimens in 35 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be u...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-30540 | biostudies-arrayexpress
TranscriptomicsGene expression signature and the prediction of lymph node metastases
Samples were taken from colorectal cancers in surgically resected specimens in 89 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be u...
ORGANISM(S): Homo sapiens 
2010-08-31 | E-GEOD-4459 | biostudies-arrayexpress
TranscriptomicsThe Function of Piwi is Independent of Its Slicer Activity
In diverse organisms, the highly-conserved Piwi proteins bind to a complex class of small non-coding RNAs called piRNAs, and are essential for germline stem cell maintenance, transposon silencing, fertility, and offspring viability1. By homology with other Argonautes, Piwi proteins have been propose...
ORGANISM(S): Drosophila melanogaster 
2013-02-04 | E-GEOD-34032 | biostudies-arrayexpress
TranscriptomicsGene expression signature and the prediction of liver metastasis in colorectal cancer by DNA microarray
Samples were taken from colorectal cancers in surgically resected specimens in 189 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes that can be ...
ORGANISM(S): Homo sapiens 
2011-08-25 | E-GEOD-14095 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis in mouse late spermatocyte deficient in pachytene piRNAs (Mov10l1 fl/+ and Mov10l1 s fl/-)
In animal germline cells, Piwi-interacting RNAs (piRNAs) silence retrotransposons through post-transcriptional and transcriptional mechanisms. However, little is known, especially in mammals, about the functions of piRNAs beyond retrotransposon suppression1-5. In mammalian spermatocytes, piRNAs are ...
ORGANISM(S): Mus musculus 
2014-11-20 | E-GEOD-43735 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis in mouse late spermatocyte deficient in pachytene piRNAs (MIWI-immunoprecipitated RNAs)
The eukaryotic genome has vast intergenic regions containing transposons, pseudogenes and other repetitive sequences. They produce numerous long non-coding RNAs (lncRNAs) and PIWI-interacting RNAs (piRNAs), yet the functions of the vast intergenic regions remain largely unknown. Mammalian piRNAs are...
ORGANISM(S): Mus musculus 
2014-11-20 | E-GEOD-62416 | biostudies-arrayexpress
UnknownTopology and Sequence-Dependent Micellization and Phase Separation of Pluronic L35, L64, 10R5, and 17R4: Effects of Cyclization and the Chain Ends.
Not available
S-EPMC9105568 | biostudies-literature
TranscriptomicsTranscriptome analysis in mouse early round spermatids deficient in pachytene piRNAs (Miwi+/- and -/-)
In animal germline cells, Piwi-interacting RNAs (piRNAs) silence retrotransposons through post-transcriptional and transcriptional mechanisms. However, little is known, especially in mammals, about the functions of piRNAs beyond retrotransposon suppression1-5. In mammalian spermatocytes, piRNAs are ...
ORGANISM(S): Mus musculus 
2014-11-20 | E-GEOD-41974 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis during mouse spermatogenic cell development
In animal germline cells, Piwi-interacting RNAs (piRNAs) silence retrotransposons through post-transcriptional and transcriptional mechanisms. However, little is known, especially in mammals, about the functions of piRNAs beyond retrotransposon suppression1-5. In mammalian spermatocytes, piRNAs are ...
ORGANISM(S): Mus musculus 
2014-11-20 | E-GEOD-41976 | biostudies-arrayexpress
TranscriptomicspiRNA analysis in Stambp-ps1 mutant mouse testes
In animal germline cells, Piwi-interacting RNAs (piRNAs) silence retrotransposons through post-transcriptional and transcriptional mechanisms. However, little is known, especially in mammals, about the functions of piRNAs beyond retrotransposon suppression1-5. In mammalian spermatocytes, piRNAs are ...
ORGANISM(S): Mus musculus 
2014-11-20 | E-GEOD-41977 | biostudies-arrayexpress
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