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MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (MS assays)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS674 | MetaboLights
MetabolomicsThe impact of nutritional supplementation on sweat metabolomic content
Sweat is emerging as a prominent biosource for real-time human performance monitoring applications. Although promising, sources of variability must be identified to truly utilize sweat for biomarker applications. In this proof-of-concept study, a targeted metabolomics method was applied to sweat col...
2021-03-15 | MTBLS2427 | MetaboLights
ProteomicsThe Staphylococcus aureus Host Cell Genetic Adhesion Network
Adhesion of Staphylococcus aureus to the host’s skin and mucosae enables asymptomatic colonization and the establishment of infections. This process is facilitated by cell wall-anchored (CWA) adhesins that are covalently attached to the bacterial cell wall and exhibit affinity for host ligands. To g...
ORGANISM(S): Staphylococcus aureus 
2023-03-04 | PXD018514 | Pride
Anti-adhesives  anti-virulence  staphylococcus aureus  mrsa  antibiotic resistance  cell wall-anchored proteins  autolysin  adhesome 
ProteomicsStress-induced interactome of the O-GlcNAcase by SILAC-BioID-MS/MS
O-linked-β-N-acetylglucosamine (O-GlcNAc) dynamically modifies and regulates thousands of nuclear, cytoplasmic, and mitochondrial proteins. Cellular stress, including oxidative stress, results in increased O-GlcNAcylation on numerous proteins and this is thought to promote cell survival. The mechani...
ORGANISM(S): Homo sapiens (Human) 
2017-03-14 | PXD005039 | Pride
Glycosylation Mgea5 Fasn Silac O-glcnac Human Bioid 
ProteomicsDiscordant Fasting Signaling Response in Hearts of Mice with Diet-Induced Obeisity and Insulin Resistance
Sixteen mouse heart samples were analyzed in four groups: Normal, 24hr fast, Diet-Induced Obesity, and DIO with 24hr fast. The cytoplasmic fractions of IN-Sequence heart preparations (solubilized proteins excluding most myofilaments) were analyzed by Liquid Chromatography coupled Mass Spectrometry...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-26 | PXD003345 | Pride
Metabolism Heart Proteomics Mouse Mass spectrometry Ms In-sequence Fvbn Fasting 
ProteomicsCalu-3 cell lipidome response to a wild type H5N1 and mutants Influenza viruses
Lipidomics data from Calu-3 cell culture; Treated with wild-type and mutant H5N1 and mockulum; Time points 0, 3, 7, 12, 18 & 24 h; 5 biological replicates
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-08-04 | MSV000080023 | MassIVE
ProteomicsHuman Calu-3 cell lipidome response to a wild type infectious clone of H7N9 and mutant H7N9 viruses
Lipidomics data from Calu-3 cell culture; Treated with wild-type and mutant H7N9 and mockulum; Time points 0, 3, 7, 12, 18 & 24 h; 5 biological replicates
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2015-11-23 | MSV000079386 | MassIVE
ProteomicsMouse lung metabolome response to a wild type infectious clone of H7N9 Influenza virus and mutants
Metabolomics data from mouse lung; Treated with wild-type and mutant H7N9 and mockulum; Time points 1, 2, 4 & 7 days; 5 biological replicates
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2015-07-31 | MSV000079206 | MassIVE
ProteomicsHuman Calu-3 cell proteome response to a wild type infectious clone of H5N1 and mutant H5N1 viruses
Lipidomics data from Calu-3 cell culture; Treated with wild-type and mutant H5N1 and mockulum; Time points 0, 3, 7, 12, 18 & 24 h; 5 biological replicates
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-01-18 | MSV000079459 | MassIVE
ProteomicsMouse lung lipidomics response to H5N1 (and mutants) and H1N1 Influenza viruses
Lipidomics data from mouse lung; Treated with wild-type and mutant H5N1, H1N1, and mockulum; Time points 1, 2, 4 & 7 days; 5 biological replicates
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-08-05 | MSV000080027 | MassIVE
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