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MetabolomicsClock regulation of metabolites reveals coupling between transcription and metabolism
The circadian clock is intricately connected with metabolism, however the precise details of these connections are incomplete. Here we used high temporal resolution metabolite profiling to determine circadian regulation of mouse liver and cell autonomous metabolism. In mouse liver, we found ~50% of ...
2017-04-05 | MTBLS292 | MetaboLights
UnknownPesticide exposure assessment for surface waters in the EU. Part 2: Determination of statistically based run-off and drainage scenarios for Germany.
Not available
S-EPMC5396381 | biostudies-literature
MetabolomicsA shotgun metabolomics approach to characterize the dissolved organic matter pool in the Samail Ophiolite aquifer
The process of serpentinization has been implicated in supporting life on both early Earth and other worlds in our Solar System. While numerous studies have provided clues to the survival strategies of microbial communities in serpentinizing environments on modern Earth, characterizing microbial act...
2023-03-02 | MTBLS6081 | MetaboLights
ProteomicsDinoflagellates contribute to primary and secondary production across biogeochemical gradients of the central Pacific Ocean
In this study we explored the metabolism of unicellular eukaryotic organisms (protists) across a 4,600 km meridional transect in the central Pacific Ocean. The region contains a natural biogeochemical gradient spanning from low nitrogen, oligotrophic waters to a productive equatorial upwelling syste...
ORGANISM(S): Phytoplankton Environmental Sample (ncbitaxon:1249885) 
2021-11-03 | MSV000088314 | MassIVE
UnknownMitigating Health Disparities After Natural Disasters: Lessons From The RISK Project.
Not available
S-EPMC8533028 | biostudies-literature
UnknownBioconcentration of Per- and Polyfluoroalkyl Substances and Precursors in Fathead Minnow Tissues Environmentally Exposed to Aqueous Film-Forming Foam-Contaminated Waters.
Not available
S-EPMC11552075 | biostudies-literature
ProteomicsD2O proteome dynamics in response to energy deficit
Energy deficit has shaped human evolution, and represents a potent physiological stressor associated with improvements in lifespan and healthspan in several species. Preserving locomotive capacity has likely been essential for food procurement and survival from starvation during the hunter-gatherer ...
ORGANISM(S): Homo sapiens (Human) 
2025-11-04 | PXD061267 | Pride
Human Deuterium oxide labelling Skeletal muscle Lc-ms/ms 
ProteomicsHuman Muscle protein responses to exercise during low carbohydrate availablility
Background. Training with low carbohydrate availability (LCA) has been proposed as an independent determinant of physiological perturbations commonly attributed to low energy availability (LEA) and to increase skeletal muscle oxidative machinery, yet the effects of LCA in isolation from LEA remain u...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD077494 | Pride
Human Myofibrillar Muscle Lc-ms/ms 
ProteomicsDeuterium oxide labeling methods for bulk and single muscle protein synthesis measures, and measures of integrated muscle protein synthesis and breakdown rates
This methodological pilot study explored the feasibility of an integrated tracer approach for simultaneous measurement of human skeletal muscle protein synthesis and breakdown during prolonged deuterium oxide (²H₂O) labelling. Four healthy men completed a five week protocol combining daily oral ²H₂O...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD078552 | Pride
Human Skeletal muscle Protein trunover 
ProteomicsStructural basis for lipid binding and function by an evolutionally conserved protein, Serum Amyloid A
Serum amyloid A (SAA) is a plasma protein that transports lipids during inflammation. To explore SAA solution conformations and lipid binding mechanism, we used hydrogen-deuterium exchange mass spectrometry, lipoprotein reconstitution, sequence analysis and molecular dynamics simulations. Solution ...
ORGANISM(S): Mus musculus (Mouse) 
2020-02-17 | PXD016391 | Pride
Hydrogen-deuterium exchange mass spectrometry  molecular dynamics simulations  lipoprotein nanoparticle  intrinsically disordered protein  β-hairpin misfolding intermediate  inflammation and immunity 
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