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TranscriptomicsTranscriptional Response to Iron Limitation in Pelagibacter ubique
We investigated the gene expression responses of Candidatus Pelagibacter ubique cultures to iron limitation. Differential expression was observed for genes in iron acquisition and incorporation operons. SfuC in particular was 16 times higher in iron-limited cultures and encodes a periplasmic iron-bi...
ORGANISM(S): Candidatus Pelagibacter ubique HTCC1062 
2010-05-05 | E-GEOD-20962 | biostudies-arrayexpress
MetabolomicsSAR11 Cells Rely on Enzyme Multifunctionality to Transport and Metabolize a Range of Polyamine Compounds
In the ocean surface layer and cell culture, the polyamine transport protein PotD of SAR11 bacteria is often one of the most abundant proteins detected. Polyamines are organic cations at seawater pH produced by all living organisms and are thought to be an important component of dissolved organic ma...
2021-09-09 | MTBLS3146 | MetaboLights
MetabolomicsMitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis
Somatic DNMT3A R882 codon mutations drive the most common form of clonal haematopoiesis (CH) and are associated with increased acute myeloid leukaemia (AML) risk1,2. Preventing expansion of DNMT3A-R882-mutant haematopoietic stem/progenitor cells (HSPCs) may therefore avert progression to AML. To ide...
2025-02-06 | MTBLS12201 | MetaboLights
TranscriptomicsGenes enabling phenotypic plasticity evolve canalized gene expression by their limited associations with transcriptional regulators
Global climate change increasingly polarizes environments, presenting unprecedented challenges to many organisms (Smol, 2012). Polarization occurs not only in the spatial dimension, producing greater desert drought and tropical rainfall, for example, but also in the temporal dimension by making a lo...
ORGANISM(S): Fundulus heteroclitus 
2014-10-02 | E-GEOD-47035 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of resistant and susceptible Atlantic salmon fry challenged with Infectious Pancreatic Necrosis virus
Infectious Pancreatic Necrosis (IPN) is a highly contagious birnavirus disease of farmed salmonid fish, which often causes high levels of morbidity and mortality. A large genetic component underlying resistance to this disease has been previously described for Atlantic salmon (Salmo salar L.), which...
ORGANISM(S): Salmo salar 
2016-04-07 | E-MTAB-4275 | biostudies-arrayexpress
ProteomicsBioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative - Streptococcus pyogenes
The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (Escherichia coli, Klebsiella pneumoniae complex, Staphylococcus aureus, Streptococcus pneumoniae and Streptococcus pyogenes, 5 strains each) using an integrated application of ge...
ORGANISM(S): Streptoccous pyogenes 
2021-07-05 | PXD020863 | Pride
Proteomics Rpmi Streptococcus pyogenes Orbitrap Lfq Sera Antibiotic resistance Sepsis Dda 
Proteomicsi. Bioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative – Escherichia coli
The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (Escherichia coli, Klebsiella pneumoniae complex, Staphylococcus aureus, Streptococcus pneumoniae and Streptococcus pyogenes, 5 strains each) using an integrated application of ge...
ORGANISM(S): Escherichia coli 
2021-07-05 | PXD020545 | Pride
Proteomics Escherichia coli Rpmi Orbitrap Lfq Sera Antibiotic resistance Sepsis Dda 
ProteomicsBioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative - Klebsiella pneumoniae complex
The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (Escherichia coli, Klebsiella pneumoniae complex, Staphylococcus aureus, Streptococcus pneumoniae and Streptococcus pyogenes, 5 strains each) using an integrated application of ge...
ORGANISM(S): Klebsiella variicola Klebsiella pneumoniae 
2021-07-05 | PXD020839 | Pride
Proteomics Rpmi Klebsiella Orbitrap Lfq Sera Antibiotic resistance Sepsis Dda 
ProteomicsBioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative - Staphylococcus aureus
The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (Escherichia coli, Klebsiella pneumoniae complex, Staphylococcus aureus, Streptococcus pneumoniae and Streptococcus pyogenes, 5 strains each) using an integrated application of ge...
ORGANISM(S): Staphylococcus aureus 
2021-07-05 | PXD020791 | Pride
Proteomics Rpmi Staphylococcus aureus Orbitrap Lfq Sera Antibiotic resistance Sepsis Dda 
ProteomicsBioplatforms Australia: Antibiotic Resistant Sepsis Pathogens Framework Initiative - Escherichia coli
The Antibiotic Resistant Sepsis Pathogens Framework Initiative aims to develop a framework dataset of 5 sepsis pathogens (5 strains each) using an integrated application of genomic, transcriptomic, metabolomic and proteomic technologies. The pathogens included in this initiative are: Escherichia col...
ORGANISM(S): Escherichia coli 
2021-07-05 | PXD016840 | Pride
Proteomics Escherichia coli Rpmi Swath Sera Antibiotic resistance Sepsis 
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