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TranscriptomicsTranscription profiling of rat chondrocytes treated with glucosamine exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1beta
Glucosamine proved to be a potent, broad-spectrum inhibitor of IL-1beta. Of the 2,813 genes whose transcription was altered by IL-1beta stimulation (p<0.0001), glucosamine significantly blocked the response in 2,055 (~73%). Glucosamine fully protected the chondrocytes from IL-1-induced expression of...
ORGANISM(S): Rattus norvegicus 
2009-04-23 | E-GEOD-6119 | biostudies-arrayexpress
TranscriptomicsRNA seq of rectal tumour tissue and paired healthy tissue, with EpCAM purification
Tumour tissue was immediately obtained post-surgery along with paired healthy tissue near (<2cm from tumour margin) and far (>10cm) from the tumour site. Each tissue was dissociated and stained with flow cytometry antibodies and sorted by FACS into Live/Dead-negative EpCAM-positive CD3-negative popu...
ORGANISM(S): Homo sapiens 
2020-02-27 | E-MTAB-8803 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of invasive breast cancer events from the tamoxifen prevention trial
Gene expression profiling of invasive breast cancer events from the tamoxifen prevention trial validates low estrogen receptor mRNA level as the main determinant of tamoxifen resistance in estrogen receptor positive breast cancer. In NSABP Breast Cancer Prevention Trial (BCPT), tamoxifen reduced th...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-12665 | biostudies-arrayexpress
UnknownAn ADAMTS3 missense variant is associated with Norwich Terrier upper airway syndrome.
Not available
S-EPMC6521993 | biostudies-literature
ProteomicsCan Blood Proteome Diversity Among Fish Species Help Explain Perfluoroalkyl Acid Trophodynamics in Aquatic Food Webs?
Per- and polyfluoroalkyl substances (PFAS) are a diverse family of industrially significant synthetic chemicals infamous for extreme environmental persistence and global environmental distribution. Many PFAS are bioaccumulative and biologically active mainly due to their tendency to bind with variou...
ORGANISM(S): Salvelinus namaycush Alosa pseudoharengus Myoxocephalus thompsonii 
2023-03-11 | PXD039145 | Pride
Shotgun proteomics Apolipoproteins Biomagnification Protein binding Pfas Albumin 
TranscriptomicsNon-Replicating Mycobacterium tuberculosis Elicits a Reduced Infectivity Profile with Corresponding Modifications to the Cell Wall and Extracellular Matrix
A key feature of Mycobacterium tuberculosis is its ability to become dormant in the host. Little is known of the mechanisms by which these bacilli are able to persist in this state. Therefore, the focus of this study was to emulate environmental conditions encountered by M. tuberculosis in the granu...
ORGANISM(S): Mycobacterium tuberculosis 
2016-11-14 | E-BUGS-142 | biostudies-arrayexpress
UnknownRNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures.
Not available
S-EPMC4436661 | biostudies-literature
UnknownSingle-agent gemcitabine in patients with advanced, pre-treated angiosarcoma: A multicenter, retrospective study.
Not available
S-EPMC9939156 | biostudies-literature
UnknownNationwide survey of coeliac disease serology testing in the UK.
Not available
S-EPMC12336569 | biostudies-literature
UnknownClimate Effects on Belowground Tea Litter Decomposition Depend on Ecosystem and Organic Matter Types in Global Wetlands.
Not available
S-EPMC11636250 | biostudies-literature
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