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UnknownBRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group.
Not available
S-EPMC3413277 | biostudies-literature
Unknownα-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.
Not available
S-EPMC3346117 | biostudies-literature
GenomicsModulation of enhancer looping and differential gene targeting by Epstein-Barr virus transcription factors directs epigenetic reprogramming
Epstein-Barr virus (EBV) epigenetically reprogrammes B-lymphocytes to drive immortalization and facilitate viral persistence. Host-cell transcription is perturbed principally through the actions of EBV EBNA 2, 3A, 3B and 3C, with cellular genes deregulated by specific combinations of these EBNAs thr...
ORGANISM(S): Homo sapiens 
2013-09-13 | E-GEOD-47629 | biostudies-arrayexpress
UnknownRNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination.
Not available
S-EPMC5678581 | biostudies-literature
UnknownAn Orphan CpG Island Drives Expression of a let-7 miRNA Precursor with an Important Role in Mouse Development.
Not available
S-EPMC6660310 | biostudies-literature
UnknownIdentical sets of methylated and nonmethylated genes in Ciona intestinalis sperm and muscle cells.
Not available
S-EPMC3827831 | biostudies-literature
TranscriptomicsProspective molecular profiling of canine cancers provides a clinically relevant comparative model for evaluating precision medicine (PMed) trials
Feasibility trial to examine the ability to conduct molecular guided therapy in a geographically distributed systems within strict time constraints Canine patients were enrolled across a broad panel of tumor types where tumor samples were acquired and processed to preserve RNA quality for genomic an...
ORGANISM(S): Canis lupus 
2014-04-28 | E-GEOD-51131 | biostudies-arrayexpress
ProteomicsSelective activation of PERK signaling mediates fibroblast education and tumor progression by a CRELD2-dependent mechanism
It is now well-accepted that cancers co-opt the microenvironment to support their growth. However, the molecular mechanisms underlying cancer-microenvironment interactions remain poorly defined. We have found that Rho-associated kinase (ROCK) activity in the epithelial component of mammary tumors se...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-27 | PXD018253 | Pride
Cancer progression Integrated stress response (isr) Unfolded protein response 25 (upr) Perk Cancer-associated fibroblasts (cafs) Breast cancer Endoplasmic reticulum (er)stress Rock 26 extracellular matrix Tumor microenvironment 
UnknownIncidence and Outcomes of Acute Kidney Injury in Patients Admitted to Hospital With COVID-19: A Retrospective Cohort Study.
Not available
S-EPMC8278450 | biostudies-literature
TranscriptomicsA timecourse of IAA treatment on the Arabidopsis root tip
A timecourse of IAA treatment on the Arabidopsis root tip
ORGANISM(S): Arabidopsis thaliana 
2013-05-12 | E-MTAB-1354 | biostudies-arrayexpress
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