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TranscriptomicsSingle-cell RNA and B cell receptor profiling of B cell response to SARS-CoV-2 vaccination
We generated single-cell transcriptomic and BCR sequencing data of B cells from peripheral blood samples taken from a SARS-CoV-2-antigen-naive cohort being vaccinated with the SARS-CoV-2 mRNA-1273 vaccine. Blood samples were collected at the baseline timepoint D-1 (i.e. one day prior to the initial ...
ORGANISM(S): Homo sapiens 
2026-05-08 | E-MTAB-16531 | biostudies-arrayexpress
UnknownCongruent Weber-B ankle fractures do not alter tibiotalar contact mechanics.
Not available
S-EPMC11538441 | biostudies-literature
TranscriptomicsAntibody repertoire RNA-seq throughout key stages of mouse B-cell development (pre-B-cells, naive B cells, plasma cells)
We sought to investigate the extent of genetic and antigen-driven predetermination of antibody repertoires throughout B-cell development (pre-B cells, naive B cells, plasma cells). To this end, we used (i) an inbred model organism (mouse, C57BL/6J) to quantify genetic predetermination and (ii) cohor...
ORGANISM(S): Mus musculus 
2017-03-28 | E-MTAB-5349 | biostudies-arrayexpress
TranscriptomicsB-cell tumor development in Tet2-deficient mice
The TET2 gene encodes an α-ketoglutarate-dependent dioxygenase able to oxidize 5-methylcytosine into 5-hydroxymethylcytosine, which is a step toward active DNA demethylation. TET2 is frequently mutated in myeloid malignancies but also in B- and T-cell malignancies. TET2 somatic mutations are also id...
ORGANISM(S): Mus musculus 
2019-12-12 | E-MTAB-8501 | biostudies-arrayexpress
TranscriptomicsscRNASeq of Naïve, GC, plasma, memory B cells sorted from WT and Fip200-deficient mice spleen
We have employed a scRANSeq to study the difference between WT and Fip200-deficient B cell populations from mice spleen 11 days after immunization. FIP200 plays an important role in regulating LC3-dependent and LC3-independent autophage pathway, which is crucial for B cell development and differenti...
ORGANISM(S): Mus musculus 
2025-11-25 | E-MTAB-16123 | biostudies-arrayexpress
ProteomicsBiogenesis of hepatitis B virus e antigen is driven by translocon-associated protein complex and regulated by conserved cysteine residues within its signal peptide sequence
Hepatitis B virus (HBV) uses e antigen (HBe) which is dispensable for virus infectivity to modulate host immune responses and to achieve viral persistence in human hepatocytes. The HBe precursor (p25) is directed to the endoplasmic reticulum (ER), where cleavage of the signal peptide (sp) gives rise...
ORGANISM(S): Homo sapiens (Human) Hepatitis B virus 
2022-07-01 | PXD025430 | Pride
Hbe Er translocation Hepatitis b virus Hbv precore protein Trap complex Signal peptide Cysteine residues 
TranscriptomicsInnate response activator B cells are sentinels that guard against polymicrobial sepsis
Innate immunity is fundamental to recognition and clearance of bacterial infection. The relevant cells and molecules that orchestrate an effective response, however, remain incompletely understood. Here we describe a previously unknown population of B cells, which we have named innate response activ...
ORGANISM(S): Mus musculus 
2012-02-07 | E-GEOD-32372 | biostudies-arrayexpress
UnknownLateral Talar Subluxation Measurements in Nonoperatively Managed Weber B Ankle Fractures.
Not available
S-EPMC10363887 | biostudies-literature
UnknownDiagnosis of tibiofibular syndesmosis instability in Weber type B malleolar fractures.
Not available
S-EPMC7370571 | biostudies-literature
UnknownWeightbearing CT Assessment of Medial Clear Space Volume Changes in Weber B Fractures: A Preliminary Analysis.
Not available
S-EPMC12477379 | biostudies-literature
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